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1/12/2026 10:07:36 AM | Browse: 1 | Download: 11
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 114818
Country Saudi Arabia
Received
2025-09-29 01:32
Peer-Review Started
2025-09-29 01:33
First Decision by Editorial Office Director
2025-10-11 03:09
Return for Revision
2025-10-11 03:09
Revised
2025-10-11 14:40
Publication Fee Transferred
Second Decision by Editor
2025-11-18 01:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-18 07:59
Articles in Press
2025-11-18 07:59
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-04 01:04
Publish the Manuscript Online
2026-01-12 10:07
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Rectal neuroendocrine tumors: Update
Manuscript Source Invited Manuscript
All Author List Mohammed Khayyat and Yasir M Khayyat
ORCID
Author(s) ORCID Number
Mohammed Khayyat http://orcid.org/0009-0008-4020-1153
Yasir M Khayyat http://orcid.org/0000-0002-8344-2028
Funding Agency and Grant Number
Corresponding Author Yasir M Khayyat, FACG, FACP, FRCP (C), Professor, Department of Medicine, Faculty of Medicine, Umm AL-Qura University, AlAwali District, Makkah 8156-24381, Saudi Arabia. ymkhayyat@uqu.edu.sa
Key Words Neuroendocrine; Rectum; Metastasis; Endoscopic ultrasound; Transanal
Core Tip This manuscript highlights that, although rare, rectal neuroendocrine tumors exhibit distinct prognostic and therapeutic profiles. Key innovations include the identification of metabolic syndrome components as risk factors, the prognostic value of vascular patterns and biomarkers such as chromogranin A as well as the refined endoscopic resection techniques showing efficacy for small tumors. Importantly, tumor grade and size are critical for predicting metastasis and survival, and local excision is often sufficient for smaller lesions.
Publish Date 2026-01-12 10:07
Citation

Khayyat M, Khayyat YM. Rectal neuroendocrine tumors: Update. World J Gastrointest Oncol 2026; 18(1): 114818

URL https://www.wjgnet.com/1948-5204/full/v18/i1/114818.htm
DOI https://dx.doi.org/10.4251/wjgo.v18.i1.114818
Full Article (PDF) WJGO-18-114818-with-cover.pdf
Manuscript File 114818_Auto_Edited_064709.docx
Answering Reviewers 114818-answering-reviewers.pdf
Audio Core Tip 114818-audio.mp3
Conflict-of-Interest Disclosure Form 114818-conflict-of-interest-statement.pdf
Copyright License Agreement 114818-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 114818-non-native-speakers.pdf
Peer-review Report 114818-peer-reviews.pdf
Scientific Misconduct Check 114818-scientific-misconduct-check.png
Scientific Editor Work List 114818-scientific-editor-work-list.pdf
CrossCheck Report 114818-crosscheck-report.pdf