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Articles Published Processes
12/16/2025 3:23:23 AM | Browse: 0 | Download: 0
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Received |
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2025-09-29 01:49 |
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Peer-Review Started |
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2025-09-29 01:49 |
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First Decision by Editorial Office Director |
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2025-10-10 09:08 |
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Return for Revision |
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2025-10-10 09:08 |
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Revised |
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2025-10-18 09:03 |
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Publication Fee Transferred |
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2025-10-20 12:45 |
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Second Decision by Editor |
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2025-11-13 02:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-11-13 07:56 |
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Articles in Press |
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2025-11-13 07:56 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-11-27 09:05 |
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Publish the Manuscript Online |
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2025-12-16 03:23 |
| ISSN |
1948-5190 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Repeated hemorrhagic ulcers of the esophagus associated with acquired hemophilia A: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Makoto Saito, Kencho Miyashita, Masahiro Ieko, Emi Yokoyama, Minoru Kanaya, Koh Izumiyama, Akio Mori, Masanobu Morioka and Takeshi Kondo |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Makoto Saito, Chief Physician, Blood Disorders Center, Aiiku Hospital, Chuo-ku Minami 4 Nishi 25, Sapporo 064-0804, Hokkaido, Japan. ikyoku@aiiku-hp.or.jp |
| Key Words |
Acquired hemophilia A; Gastrointestinal bleeding; Esophageal ulcer; Endoscopic hemostasis; Bypass hemostatic agent; Emicizumab; Case report |
| Core Tip |
Acquired hemophilia A can cause life-threatening, severe bleeding. Most cases are characterized by subcutaneous or intramuscular bleeding, whereas gastrointestinal hemorrhage is rare. We report the case of a 76-year-old woman with AHA who presented with repeated bleeding from an esophageal ulcer. Endoscopic hemostasis using radiofrequency ablation was performed seven times; however, this procedure was unsuccessful. First, a mixture of factors VIIa and X (a bypass hemostatic agent) was administered, successfully controlling the hemorrhage from the esophageal ulcer. In addition, emicizumab (a substitute for activated factor VIII) was administered, after which no further bleeding was observed. |
| Publish Date |
2025-12-16 03:23 |
| Citation |
Saito M, Miyashita K, Ieko M, Yokoyama E, Kanaya M, Izumiyama K, Mori A, Morioka M, Kondo T. Repeated hemorrhagic ulcers of the esophagus associated with acquired hemophilia A: A case report. World J Gastrointest Endosc 2025; 17(12): 114836 |
| URL |
https://www.wjgnet.com/1948-5190/full/v17/i12/114836.htm |
| DOI |
https://dx.doi.org/10.4253/wjge.v17.i12.114836 |
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