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Articles Published Processes
5/29/2026 8:41:42 AM | Browse: 4 | Download: 11
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Received |
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2025-09-29 01:46 |
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Peer-Review Started |
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2025-09-29 01:46 |
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First Decision by Editorial Office Director |
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2025-12-03 10:12 |
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Return for Revision |
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2025-12-03 10:12 |
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Revised |
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2025-12-04 17:49 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-06 02:39 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-07 02:11 |
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Articles in Press |
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2026-01-07 02:11 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-05-20 01:10 |
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Publish the Manuscript Online |
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2026-05-29 08:41 |
| ISSN |
2220-3230 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Editorial |
| Article Title |
Navigating liver transplantation after malabsorptive bariatric surgery – A new risk of rejection
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Toshifumi Yodoshi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Toshifumi Yodoshi, MD, PhD, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229, United States. toshifumi.yodoshi@cchmc.org |
| Key Words |
Metabolic dysfunction-associated steatotic liver disease; Liver fibrosis; Liver transplantation; Bariatric surgery; Acute cellular rejection; Immunosuppression management; Therapeutic drug monitoring |
| Core Tip |
Malabsorptive bariatric surgery (for example, Roux‑en‑Y gastric bypass and duodenal switch) is increasingly common among liver transplant candidates. Chang et al. report significantly higher rates, frequency, and earlier onset of biopsy‑proven acute cellular rejection in recipients with prior malabsorptive anatomy, despite comparable perioperative outcomes and one‑year survival. This editorial explores plausible mechanisms—especially impaired absorption of oral immunosuppressants—and outlines pragmatic strategies: intensified therapeutic drug monitoring, dose and formulation adjustments (including extended‑release tacrolimus), and multidisciplinary nutrition–pharmacy support to reduce rejection and protect long‑term graft function. |
| Publish Date |
2026-05-29 08:41 |
| Citation |
Yodoshi T. Navigating liver transplantation after malabsorptive bariatric surgery – A new risk of rejection. World J Transplant 2026; 16(2): 114837 |
| URL |
https://www.wjgnet.com/2220-3230/full/v16/i2/114837.htm |
| DOI |
https://dx.doi.org/10.5500/wjt.v16.i2.114837 |
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