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5/27/2026 8:10:54 AM | Browse: 2 | Download: 16
Publication Name World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID 114876
Country Algeria
Received
2025-10-01 01:50
Peer-Review Started
2025-10-01 01:50
First Decision by Editorial Office Director
2025-10-11 03:30
Return for Revision
2025-10-11 03:30
Revised
2025-12-02 00:20
Publication Fee Transferred
Second Decision by Editor
2026-02-03 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-03 03:54
Articles in Press
2026-02-03 03:54
Edit the Manuscript by Language Editor
2026-02-10 22:17
Typeset the Manuscript
2026-05-14 01:12
Publish the Manuscript Online
2026-05-27 08:10
ISSN 2150-5349 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Prospective Study
Article Title Effect of cholecystectomy on liver fat and fibrosis in metabolic dysfunction-associated steatotic liver disease patients
Manuscript Source Invited Manuscript
All Author List Khellaf Amalou, Nassila Belal, Abdelghani Tibouk, Yasmine Ghedada, Rym Rekab, Sabrina Fadel, Nabil Debzi and Abderezak Bousloub
ORCID
Author(s) ORCID Number
Khellaf Amalou http://orcid.org/0000-0003-2626-0815
Funding Agency and Grant Number
Corresponding Author Khellaf Amalou, Assistant Professor, PhD, Department of Gastroenterology, Mohamed Seghir Nekkache, Kouba 246, Algiers 16000, Algeria. amalou_kh@yahoo.fr
Key Words Metabolic dysfunction-associated steatotic liver disease; Cholecystectomy; Hepatic fibrosis; Metabolic dysfunction-associated steatotic liver; Metabolic dysfunction-associated steatohepatitis
Core Tip Metabolic dysfunction-associated steatotic liver disease (MASLD) has emerged as the most common chronic liver disease. It is significantly linked to diabetes, obesity, and other cardiometabolic risk factors. It is more pronounced in cholecystectomized patients than in those with lithiasis. Recent research suggests that the gallbladder may help to maintain overall metabolic homeostasis. Recent data suggests that cholecystectomy (Chx) has metabolic effects and may operate as a risk factor for MASLD and metabolic syndrome. In our study, we found that Chx enhances metabolic dysfunction-associated steatotic liver and fibrosis. MASLD prevalence is higher in the Chx group than in the general population.
Publish Date 2026-05-27 08:10
Citation

Amalou K, Belal N, Tibouk A, Ghedada Y, Rekab R, Fadel S, Debzi N, Bousloub A. Effect of cholecystectomy on liver fat and fibrosis in metabolic dysfunction-associated steatotic liver disease patients. World J Gastrointest Pharmacol Ther 2026; 17(2): 114876

URL https://www.wjgnet.com/2150-5349/full/v17/i2/114876.htm
DOI https://dx.doi.org/10.4292/wjgpt.v17.i2.114876
Full Article (PDF) WJGPT-17-114876-with-cover.pdf
CONSORT 2010 Statement 114876-CONSORT-2010-statement.pdf
Manuscript File 114876_Auto_Edited_073253.docx
Answering Reviewers 114876-answering-reviewers.pdf
Audio Core Tip 114876-audio.m4a
Biostatistics Review Certificate 114876-biostatistics-statement.pdf
Clinical Trial Registration Statement 114876-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 114876-conflict-of-interest-statement.pdf
Copyright License Agreement 114876-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 114876-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 114876-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 114876-non-native-speakers.pdf
Peer-review Report 114876-peer-reviews.pdf
Scientific Misconduct Check 114876-scientific-misconduct-check.png
Scientific Editor Work List 114876-scientific-editor-work-list.pdf
CrossCheck Report 114876-crosscheck-report.pdf