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Articles Published Processes
2/6/2026 8:43:38 AM | Browse: 1 | Download: 12
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Received |
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2025-10-09 00:18 |
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Peer-Review Started |
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2025-10-10 00:07 |
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First Decision by Editorial Office Director |
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2025-11-24 12:10 |
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Return for Revision |
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2025-11-24 12:10 |
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Revised |
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2025-11-25 12:56 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-04 02:47 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-04 06:15 |
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Articles in Press |
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2026-01-04 06:15 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-01-27 02:32 |
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Publish the Manuscript Online |
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2026-02-06 08:43 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Ophthalmology |
| Manuscript Type |
Editorial |
| Article Title |
Corneal neuropathy: An overlooked biomarker for dry eye in type 2 diabetes
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Marco Zeppieri, Matteo Capobianco, Federico Visalli, Marieme Khouyyi, Caterina Gagliano and Francesco Cappellani |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Marco Zeppieri, Consultant, MD, PhD, Department of Ophthalmology, University Hospital of Udine, p. le S. Maria della Misericordia 15, Udine 33100, Italy. mark.zeppieri@asufc.sanita.fvg.it |
| Key Words |
Type 2 diabetes; Corneal neuropathy; Dry eye syndrome; Ocular surface disease biomarkers; Inflammatory biomarkers; Oxidative stress; Precision medicine |
| Core Tip |
Dry eye disease in type 2 diabetes is not merely a surface ocular issue; it signifies underlying neurovascular and metabolic impairment. Han et al’s paper presents data correlating corneal nerve modifications with the severity of dry eye disease in patients with type 2 diabetes. Together with expanding findings on inflammatory biomarkers, immunological cross-talk, and global research trends, this body of evidence highlights the necessity to include ocular surface assessment into diabetes therapy. Future advancements will depend on precision medicine approaches, biomarker-directed screening, and medicines aimed at neuroinflammation and oxidative stress to maintain eyesight and enhance quality of life. |
| Publish Date |
2026-02-06 08:43 |
| Citation |
Zeppieri M, Capobianco M, Visalli F, Khouyyi M, Gagliano C, Cappellani F. Corneal neuropathy: An overlooked biomarker for dry eye in type 2 diabetes. World J Diabetes 2026; 17(2): 114900 |
| URL |
https://www.wjgnet.com/1948-9358/full/v17/i2/114900.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v17.i2.114900 |
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