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Articles Published Processes
11/19/2014 10:25:00 AM | Browse: 1267 | Download: 1270
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Received |
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2014-05-24 10:00 |
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Peer-Review Started |
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2014-05-24 22:57 |
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To Make the First Decision |
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2014-06-18 18:37 |
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Return for Revision |
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2014-06-19 11:01 |
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Revised |
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2014-07-01 04:54 |
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Second Decision |
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2014-09-10 13:42 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-09-10 14:04 |
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Articles in Press |
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2014-09-10 14:04 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-10-31 18:41 |
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Publish the Manuscript Online |
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2014-11-19 10:25 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Review |
Article Title |
Alterations of the gut microbiome and metabolome in alcoholic liver disease
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Manuscript Source |
Invited Manuscript |
All Author List |
Wei Zhong and Zhanxiang Zhou |
Funding Agency and Grant Number |
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Corresponding Author |
Zhanxiang Zhou, Professor, Center for Translational Biomedical Research, University of North Carolina at Greensboro, North Carolina Research Campus, 500 Laureate Way, Suite 4226, Kannapolis, NC 28081, United States. z_zhou@uncg.edu |
Key Words |
Alcoholic liver disease; Microbiome; Gut metabolome |
Core Tip |
Excessive alcohol consumption causes alcoholic liver disease (ALD) with the mechanisms of pathogenesis largely unknown. Alterations of gut microbiota and metabolites are critical contributors to the development of ALD, which may lead to identification of therapeutic targets for ALD. This review summarizes recent findings of how alcohol-induced alterations of gut microbiota and metabolome, and discusses the mechanistic link between gastrointestinal dyshomeostasis and alcoholic liver injury. |
Publish Date |
2014-11-19 10:25 |
Citation |
Zhong W, Zhou Z. Alterations of the gut microbiome and metabolome in alcoholic liver disease. World J Gastrointest Pathophysiol 2014; 5(4): 514-522 |
URL |
http://www.wjgnet.com/2150-5330/full/v5/i4/514.htm |
DOI |
http://dx.doi.org/10.4291/wjgp.v5.i4.514 |
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