BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
2/14/2026 6:34:08 AM | Browse: 57 | Download: 185
 |
Received |
|
2025-10-11 09:07 |
|
Peer-Review Started |
|
2025-10-11 09:07 |
|
First Decision by Editorial Office Director |
|
2025-10-29 08:18 |
|
Return for Revision |
|
2025-10-29 08:18 |
|
Revised |
|
2025-11-10 08:58 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2026-01-15 02:37 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2026-01-15 10:13 |
|
Articles in Press |
|
2026-01-15 10:13 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2026-02-04 02:24 |
|
Publish the Manuscript Online |
|
2026-02-14 06:34 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Editorial |
| Article Title |
Sclerostin silencing in human umbilical cord mesenchymal stem cells enhances bone regeneration via Wnt pathway activation
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Prashasti Sharma and Dharmendra Kumar Maurya |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Dharmendra Kumar Maurya, PhD, Radiation Biology & Health Sciences Division, Bhabha Atomic Research Centre, 3-82-S, A-Block, Modular Laboratory, Mumbai 400085, Maharashtra, India. dkmaurya@barc.gov.in |
| Key Words |
Sclerostin; Mesenchymal stem cells; Wnt signaling pathway; Osteogenesis; Avascular necrosis; Glucocorticoid-induced bone disease |
| Core Tip |
Silencing sclerostin in human umbilical cord mesenchymal stem cells enhances their bone-regenerative potential by activating the Wnt/β-catenin signaling pathway, providing a novel therapeutic approach for steroid-induced avascular necrosis of the femoral head. In the study by Lv et al, sh-human umbilical cord mesenchymal stem cells demonstrated better osteogenesis, suppressed adipogenesis, and improved bone architecture in a steroid-induced rat model compared to unmodified cells. |
| Publish Date |
2026-02-14 06:34 |
| Citation |
Sharma P, Maurya DK. Sclerostin silencing in human umbilical cord mesenchymal stem cells enhances bone regeneration via Wnt pathway activation. World J Stem Cells 2026; 18(2): 114980 |
| URL |
https://www.wjgnet.com/1948-0210/full/v18/i2/114980.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v18.i2.114980 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
