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Articles Published Processes
2/14/2026 6:34:08 AM | Browse: 0 | Download: 0
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Received |
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2025-10-11 09:07 |
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Peer-Review Started |
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2025-10-11 09:07 |
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First Decision by Editorial Office Director |
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2025-10-29 08:18 |
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Return for Revision |
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2025-10-29 08:18 |
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Revised |
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2025-11-10 08:58 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-15 02:37 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-15 10:13 |
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Articles in Press |
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2026-01-15 10:13 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-02-04 02:24 |
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Publish the Manuscript Online |
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2026-02-14 06:34 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Editorial |
| Article Title |
Sclerostin silencing in human umbilical cord mesenchymal stem cells enhances bone regeneration via Wnt pathway activation
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Prashasti Sharma and Dharmendra Kumar Maurya |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Dharmendra Kumar Maurya, PhD, Radiation Biology & Health Sciences Division, Bhabha Atomic Research Centre, 3-82-S, A-Block, Modular Laboratory, Mumbai 400085, Maharashtra, India. dkmaurya@barc.gov.in |
| Key Words |
Sclerostin; Mesenchymal stem cells; Wnt signaling pathway; Osteogenesis; Avascular necrosis; Glucocorticoid-induced bone disease |
| Core Tip |
Silencing sclerostin in human umbilical cord mesenchymal stem cells enhances their bone-regenerative potential by activating the Wnt/β-catenin signaling pathway, providing a novel therapeutic approach for steroid-induced avascular necrosis of the femoral head. In the study by Lv et al, sh-human umbilical cord mesenchymal stem cells demonstrated better osteogenesis, suppressed adipogenesis, and improved bone architecture in a steroid-induced rat model compared to unmodified cells. |
| Publish Date |
2026-02-14 06:34 |
| Citation |
Sharma P, Maurya DK. Sclerostin silencing in human umbilical cord mesenchymal stem cells enhances bone regeneration via Wnt pathway activation. World J Stem Cells 2026; 18(2): 114980 |
| URL |
https://www.wjgnet.com/1948-0210/full/v18/i2/114980.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v18.i2.114980 |
© 1993-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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