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2/3/2026 6:28:04 AM | Browse: 0 | Download: 0
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 114981
Country China
Received
2025-10-09 02:26
Peer-Review Started
2025-10-09 02:27
First Decision by Editorial Office Director
2025-11-05 07:44
Return for Revision
2025-11-05 07:44
Revised
2025-11-10 03:13
Publication Fee Transferred
Second Decision by Editor
2025-11-25 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-25 05:54
Articles in Press
2025-11-25 05:54
Edit the Manuscript by Language Editor
2025-11-27 02:00
Typeset the Manuscript
2026-01-26 05:54
Publish the Manuscript Online
2026-02-03 06:28
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Editorial
Article Title Radiomics-based model for predicting neoadjuvant therapy response in esophageal cancer: Limitations and suggestions
Manuscript Source Invited Manuscript
All Author List Zong-Xian Zhao
ORCID
Author(s) ORCID Number
Zong-Xian Zhao http://orcid.org/0000-0001-7553-2085
Funding Agency and Grant Number
Corresponding Author Zong-Xian Zhao, MD, Department of Anorectal Surgery, Fuyang People’s Hospital, No. 501 Sanqing Road, Yingzhou District, Fuyang 236000, Anhui Province, China. 461901580@qq.com
Key Words Esophageal cancer; Neoadjuvant therapy; Magnetic resonance imaging; Radiomics; Predictive model; Limitations
Core Tip Accurate prediction of neoadjuvant therapy response in esophageal cancer (EC) is critical to avoid ineffective treatment. Yang et al developed a non-invasive T2-weighted magnetic resonance imaging (T2WI)-radiomics model but with key limitations. These limitations include single-center, small-sample retrospective design, exclusive reliance on T2WI sequences, inadequate stability of manual segmentation, and insufficient clinical interpretability. Corresponding optimization suggestions are proposed in this editorial. Only through multicenter validation, multidisciplinary collaboration, and multimodal integration can radiomics-based machine learning models be truly translated into clinical practice, thereby supporting personalized treatment decision-making for patients with EC.
Publish Date 2026-02-03 06:28
Citation

Zhao ZX. Radiomics-based model for predicting neoadjuvant therapy response in esophageal cancer: Limitations and suggestions. World J Gastrointest Oncol 2026; 18(2): 114981

URL https://www.wjgnet.com/1948-5204/full/v18/i2/114981.htm
DOI https://dx.doi.org/10.4251/wjgo.v18.i2.114981
Full Article (PDF) WJGO-18-114981-with-cover.pdf
Manuscript File 114981_Auto_Edited_074953.docx
Answering Reviewers 114981-answering-reviewers.pdf
Audio Core Tip 114981-audio.m4a
Conflict-of-Interest Disclosure Form 114981-conflict-of-interest-statement.pdf
Copyright License Agreement 114981-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 114981-non-native-speakers.pdf
Peer-review Report 114981-peer-reviews.pdf
Scientific Misconduct Check 114981-scientific-misconduct-check.png
Scientific Editor Work List 114981-scientific-editor-work-list.pdf
CrossCheck Report 114981-crosscheck-report.pdf