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Articles Published Processes
2/26/2026 10:19:30 AM | Browse: 4 | Download: 1
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Received |
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2025-10-09 17:11 |
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Peer-Review Started |
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2025-10-09 17:11 |
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First Decision by Editorial Office Director |
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2025-11-05 05:58 |
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Return for Revision |
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2025-11-05 05:58 |
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Revised |
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2025-11-06 10:38 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-12-05 02:34 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-05 09:44 |
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Articles in Press |
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2025-12-05 09:44 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-02-05 01:05 |
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Publish the Manuscript Online |
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2026-02-26 10:19 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Review |
| Article Title |
Protective effect of ischemic preconditioning against hepatic ischemia-reperfusion injury and associated remote organ damage
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Christina Mouratidou, Efstathios T Pavlidis, Georgios Katsanos, Serafeim-Chrysovalantis Kotoulas, Athanasios Kofinas, Alexandra G Marneri, Eleni Massa, Georgios Tsoulfas, Ioannis N Galanis and Theodoros E Pavlidis |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Theodoros E Pavlidis, MD, PhD, Professor Emeritus, The Second Department of Propaedeutic Surgery, Hippokration General Hospital, School of Medicine, Aristotle University of Thessaloniki, Konstantinoupoleos 49, Thessaloniki 54642, Greece. pavlidth@auth.gr |
| Key Words |
Hepatic ischemia-reperfusion injury; Remote organ damage; Systemic inflammatory response; Ischemic preconditioning; Liver transplantation; Protective method; Pathophysiological mechanisms |
| Core Tip |
Hepatic ischemia-reperfusion injury remains a critical challenge in liver surgery and transplantation and results in increased postoperative morbidity and mortality. The complexity of the underlying pathophysiological mechanisms makes liver damage difficult to manage. Ischemic preconditioning is a promising protective strategy that limits hepatic injury while providing systemic benefits through the regulation of oxidative stress, the inflammatory response, and programmed cell death pathways. By offering protection to remote organs, ischemic preconditioning has the potential to enhance the outcomes of transplantation and other high-risk procedures, although further studies are needed to establish optimal clinical protocols. |
| Publish Date |
2026-02-26 10:19 |
| Citation |
Mouratidou C, Pavlidis ET, Katsanos G, Kotoulas SC, Kofinas A, Marneri AG, Massa E, Tsoulfas G, Galanis IN, Pavlidis TE. Protective effect of ischemic preconditioning against hepatic ischemia-reperfusion injury and associated remote organ damage. World J Gastrointest Surg 2026; 18(2): 114997 |
| URL |
https://www.wjgnet.com/1948-9366/full/v18/i2/114997.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v18.i2.114997 |
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