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2/3/2026 6:28:04 AM | Browse: 2 | Download: 13
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 115010
Country China
Received
2025-10-09 02:51
Peer-Review Started
2025-10-09 02:51
First Decision by Editorial Office Director
2025-10-28 09:43
Return for Revision
2025-10-28 09:43
Revised
2025-11-05 08:05
Publication Fee Transferred
Second Decision by Editor
2025-11-27 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-27 07:55
Articles in Press
2025-11-27 07:55
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-26 05:56
Publish the Manuscript Online
2026-02-03 06:28
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Letter to the Editor
Article Title Microbiota-metabolite signatures in metastatic colorectal cancer: Promise, pitfalls, and the path forward
Manuscript Source Invited Manuscript
All Author List Ting-Ting Zhang, Juan Yao and Han-Meng Zhang
ORCID
Author(s) ORCID Number
Juan Yao http://orcid.org/0000-0001-8515-9106
Han-Meng Zhang http://orcid.org/0009-0004-6692-0341
Funding Agency and Grant Number
Corresponding Author Han-Meng Zhang, MD, Department of Oncology, Huai’an Hospital of Huai’an City, No. 19 Shanyang Avenue, Huai’an 223299, Jiangsu Province, China. 15380666158@163.com
Key Words Colorectal cancer; Gut microbiota; Metastasis; Metabolomics; 16S rRNA sequencing; Microbial diversity; Differential metabolites; Cancer progression; Metabolic pathways; Diagnostic biomarkers
Core Tip Deng et al explores the role of gut microbiota and metabolites in colorectal cancer (CRC) metastasis using 16S rRNA sequencing and liquid chromatography-mass spectrometry-based metabolomics. It identifies significant differences in microbial communities and metabolites between metastatic and non-metastatic CRC patients. The findings suggest that specific microbial taxa and metabolites may contribute to metastasis progression, offering potential biomarkers for diagnosis and treatment. Despite some limitations, such as small sample size and cross-sectional design, the study provides valuable insights into the microbiota-metabolite axis and its potential for therapeutic targeting in CRC.
Publish Date 2026-02-03 06:28
Citation

Zhang TT, Yao J, Zhang HM. Microbiota-metabolite signatures in metastatic colorectal cancer: Promise, pitfalls, and the path forward. World J Gastrointest Oncol 2026; 18(2): 115010

URL https://www.wjgnet.com/1948-5204/full/v18/i2/115010.htm
DOI https://dx.doi.org/10.4251/wjgo.v18.i2.115010
Full Article (PDF) WJGO-18-115010-with-cover.pdf
Manuscript File 115010_Auto_Edited_074850.docx
Answering Reviewers 115010-answering-reviewers.pdf
Audio Core Tip 115010-audio.m4a
Conflict-of-Interest Disclosure Form 115010-conflict-of-interest-statement.pdf
Copyright License Agreement 115010-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 115010-non-native-speakers.pdf
Peer-review Report 115010-peer-reviews.pdf
Scientific Misconduct Check 115010-scientific-misconduct-check.png
Scientific Editor Work List 115010-scientific-editor-work-list.pdf
CrossCheck Report 115010-crosscheck-report.pdf