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3/14/2026 4:49:27 AM | Browse: 73 | Download: 250
Publication Name World Journal of Nephrology
Manuscript ID 115039
Country France
Received
2025-10-09 17:09
Peer-Review Started
2025-10-09 17:09
First Decision by Editorial Office Director
2025-10-21 07:39
Return for Revision
2025-10-21 07:39
Revised
2025-10-27 20:32
Publication Fee Transferred
Second Decision by Editor
2026-01-07 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-07 09:49
Articles in Press
2026-01-07 09:49
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-28 12:17
Publish the Manuscript Online
2026-03-14 04:49
ISSN 2220-6124 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Biology
Manuscript Type Minireviews
Article Title Effects of micro and nano plastics on renal health
Manuscript Source Invited Manuscript
All Author List Jean Demarquoy
ORCID
Author(s) ORCID Number
Jean Demarquoy http://orcid.org/0000-0002-0787-219X
Funding Agency and Grant Number
Corresponding Author Jean Demarquoy, PhD, Université de Bourgogne Europe, Institut Agro-INRAe, 6 blvd Gabriel, Dijon 21000, France. jean.demarquoy@u-bourgogne.fr
Key Words Microplastics; Kidney; Nephrotoxicity; Ferroptosis; Pyroptosis; Oxidative stress; Co-exposure; Dialysis; Environmental health
Core Tip Microplastics and nanoplastics are emerging environmental contaminants capable of reaching the human kidney through ingestion, inhalation, and medical exposure. Experimental data reveal that microplastics accumulate in renal tissue, inducing oxidative stress, endoplasmic reticulum stress, inflammation, autophagy, and ferroptosis. Co-exposure with metals or plastic additives enhances nephrotoxicity, while early human findings confirm their presence in kidney tissue and dialysis fluids. This review integrates mechanistic, experimental, and clinical evidence, highlighting the kidney as a vulnerable target organ and calling for standardized detection methods, multi-omics approaches, and biomonitoring to assess the health burden of plastic exposure.
Publish Date 2026-03-14 04:49
Citation

Demarquoy J. Effects of micro and nano plastics on renal health. World J Nephrol 2026; 15(1): 115039

URL https://www.wjgnet.com/2220-6124/full/v15/i1/115039.htm
DOI https://dx.doi.org/10.5527/wjn.v15.i1.115039
Full Article (PDF) WJN-15-115039-with-cover.pdf