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12/25/2025 9:13:56 AM | Browse: 1 | Download: 0
Publication Name World Journal of Virology
Manuscript ID 115071
Country Sri Lanka
Received
2025-10-13 07:30
Peer-Review Started
2025-10-13 07:30
First Decision by Editorial Office Director
2025-11-14 07:02
Return for Revision
2025-11-14 07:02
Revised
2025-11-19 15:38
Publication Fee Transferred
Second Decision by Editor
2025-12-11 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-11 09:07
Articles in Press
2025-12-11 09:07
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-12-19 01:46
Publish the Manuscript Online
2025-12-25 09:13
ISSN 2220-3249 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Virology
Manuscript Type Retrospective Study
Article Title Detection of dengue virus encephalitis in central part of Sri Lanka
Manuscript Source Invited Manuscript
All Author List Inuri Perera, Achini Weerathunga, Nipuni Arachchige, Lakmali Rajamanthri, Sachini Fernando and Rohitha Muthugala
ORCID
Author(s) ORCID Number
Rohitha Muthugala http://orcid.org/0000-0002-7546-1069
Funding Agency and Grant Number
Corresponding Author Rohitha Muthugala, Consultant, MD, Department of Molecular Biology, Medical Research Institute, No. 527 Dr. Danister De Silva Mawatha, Colombo 00800, Western, Sri Lanka. rohithavm@yahoo.com
Key Words Flavivirus; Central nervous system infections; Neurotropic viruses; Dengue; Sri Lanka
Core Tip Encephalitis due to arbovirus infections is a significant public health problem in tropical Asia. Encephalitis is caused by wide range of neurotropic pathogens, and flaviviruses are one of the main causative agents in tropics. Sri Lanka reports a considerable number of central nervous system infections annually. Both dengue and Japanese encephalitis are endemic, and cases of Zika and West Nile virus infections were reported in Sri Lanka. This study describes dengue virus (DENV) infections in clinically suspected patients with encephalitis in the central part of the country. A retrospective observational analysis was conducted on 99 cerebrospinal fluid samples. One sample was positive for dengue serotype 3 RNA and five samples were positive for dengue immunoglobulin M indicating recent DENV infections. These findings highlight the presence of DENV central nervous system infections and emphasize the need for broader surveillance and advanced diagnostics in future.
Publish Date 2025-12-25 09:13
Citation

Perera I, Weerathunga A, Arachchige N, Rajamanthri L, Fernando S, Muthugala R. Detection of dengue virus encephalitis in central part of Sri Lanka. World J Virol 2025; 14(4): 115071

URL https://www.wjgnet.com/2220-3249/full/v14/i4/115071.htm
DOI https://dx.doi.org/10.5501/wjv.v14.i4.115071
Full Article (PDF) WJV-14-115071-with-cover.pdf
Manuscript File 115071_Auto_Edited_011438.docx
Answering Reviewers 115071-answering-reviewers.pdf
Audio Core Tip 115071-audio.aac
Biostatistics Review Certificate 115071-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 115071-conflict-of-interest-statement.pdf
Copyright License Agreement 115071-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 115071-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 115071-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 115071-non-native-speakers.pdf
Peer-review Report 115071-peer-reviews.pdf
Scientific Misconduct Check 115071-scientific-misconduct-check.png
Scientific Editor Work List 115071-scientific-editor-work-list.pdf
CrossCheck Report 115071-crosscheck-report.pdf