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Articles Published Processes
2/11/2026 7:19:24 AM | Browse: 5 | Download: 17
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Received |
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2025-10-15 08:57 |
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Peer-Review Started |
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2025-10-15 08:58 |
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First Decision by Editorial Office Director |
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2025-11-11 09:53 |
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Return for Revision |
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2025-11-11 09:53 |
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Revised |
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2025-11-24 11:51 |
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Publication Fee Transferred |
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2025-11-26 04:24 |
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Second Decision by Editor |
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2025-12-12 02:35 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-12 07:29 |
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Articles in Press |
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2025-12-12 07:29 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-02-04 18:37 |
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Publish the Manuscript Online |
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2026-02-11 07:19 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Xing-Pi-Qing-Gan decoction alleviates alcoholic liver disease by down-regulating DDIT3 and restoring Nrf2/HO-1 antioxidant signaling: Multi-omics and experimental evidence
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Na-Fei Huang, Ping Ling, Yu-Jie Xu, Xiao-Feng Feng, Yi Zheng and Tao Sun |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Zhejiang Province |
ZCLQN25H2703 |
| Zhejiang TCM Science and Technology Plan |
2025ZR126 |
| the Science and Technology Department of the National Administration of Traditional Chinese Medicine - Administration of Traditional Chinese Medicine of Zhejiang Province Jointly Established Science and Technology Plan Project |
GZY-ZJ-KJ-24071 |
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| Corresponding Author |
Tao Sun, Associate Chief Physician, MD, The Second Affiliated Hospital of Zhejiang Chinese Medical University, The Second Affiliated Hospital of Zhejiang Chinese Medical University, The Second Affiliated Hospital of Zhejiang Chinese Medical University, No. 318, Chaowang Road, Gongshu Distric, Hangzhou, Hangzhou 310005, Zhejiang Province, China. 20171075@zcmu.edu.cn |
| Key Words |
Alcoholic liver disease; Xing-Pi-Qing-Gan decoction; DDIT3; Nrf2/HO-1; Oxidative stress |
| Core Tip |
Xing-Pi-Qing-Gan decoction (XPQG) is effective in improving ethanol-induced acute liver injury. XPQG alleviates alcoholic liver disease by suppressing DDIT3 and enhancing Nrf2/HO-1-mediated antioxidant responses, reduce lipid accumulation, inflammation, and apoptosis, as validated through multi-omics and experimental studies. |
| Publish Date |
2026-02-11 07:19 |
| Citation |
Huang NF, Ling P, Xu YJ, Feng XF, Zheng Y, Sun T. Xing-Pi-Qing-Gan decoction alleviates alcoholic liver disease by down-regulating DDIT3 and restoring Nrf2/HO-1 antioxidant signaling: Multi-omics and experimental evidence. World J Gastroenterol 2026; 32(8): 115077 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i8/115077.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i8.115077 |
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