Publication Name	World Journal of Methodology
Manuscript ID	11514
Country	Cyprus

Received	2014-05-26 18:08
Peer-Review Started	2014-05-26 22:57
To Make the First Decision	2014-07-18 12:38
Return for Revision	2014-07-18 15:10
Revised	2014-07-22 20:41
Second Decision	2014-10-16 15:14
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-10-16 15:57
Articles in Press	2014-10-16 15:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-12-11 18:42
Publish the Manuscript Online	2014-12-23 15:34

ISSN	2222-0682 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Pharmacology & Pharmacy
Manuscript Type	Review
Article Title	Transition of Thalassaemia and Friedreich ataxia from fatal to chronic diseases
Manuscript Source	Invited Manuscript
All Author List	Annita Kolnagou, Christina N Kontoghiorghe and George J Kontoghiorghes
Funding Agency and Grant Number
Corresponding Author	George J Kontoghiorghes, PhD, Professor, Postgraduate Research Institute of Science, Technology, Environment and Medicine, 3 Ammochostou Street, Limassol 3021, Cyprus. kontoghiorghes.g.j@pri.ac.cy
Key Words	Thalassaemia; Friedreich ataxia; Prenatal diagnosis; Survival; Chelation therapy; Deferiprone; Deferoxamine; Cyprus
Core Tip	Thalassaemia major (TM) and Friedreich’s ataxia (FA) are inherited diseases related to iron toxicity, with high morbidity and mortality rates. Cyprus has the highest frequency of TM and FA worldwide. Prenatal diagnosis and other health policies almost abolished the birth of TM and FA patients in Cyprus. Deferiprone has increased the survival and quality of life of TM patients, who are now reaching normal life expectancy and it is also promising for FA patients. Personalised treatments are proposed for TM and FA. The Cyprus experience can be used as a paradigm for the prevention and treatment of TM worldwide.
Publish Date	2014-12-23 15:34
Citation	Kolnagou A, Kontoghiorghe CN, Kontoghiorghes GJ. Transition of Thalassaemia and Friedreich ataxia from fatal to chronic diseases. World J Methodol 2014; 4(4): 197-218
URL	http://www.wjgnet.com/2222-0682/full/v4/i4/197.htm
DOI	http://dx.doi.org/10.5662/wjm.v4.i4.197

Full Article (PDF)	WJM-4-197.pdf
Full Article (Word)	WJM-4-197.doc
Manuscript File	11514-Review.doc
Answering Reviewers	11514-Answering reviewers.pdf
Copyright License Agreement	11514-Copyright assignment.pdf
Peer-review Report	11514-Peer review(s).pdf
Scientific Misconduct Check	11514-CrossCheck.jpg
Scientific Editor Work List	11514-Scientific editor work list.pdf