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3/2/2026 8:37:16 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 115167
Country Japan
Received
2025-10-14 03:29
Peer-Review Started
2025-10-14 03:29
First Decision by Editorial Office Director
2025-11-19 10:37
Return for Revision
2025-11-19 10:37
Revised
2025-12-05 15:33
Publication Fee Transferred
Second Decision by Editor
2026-01-16 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-16 08:59
Articles in Press
2026-01-16 08:59
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-13 00:35
Publish the Manuscript Online
2026-03-02 08:37
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Vasopressin and fluid retention after liver resection: Comparison with the renin-angiotensin-aldosterone system by surgical extent and liver function
Manuscript Source Unsolicited Manuscript
All Author List Yuto Aoki, Youich Kawano, Ryo Ga, Kazuhiko Endo, Junji Ueda, Tetsuya Shimizu and Hiroshi Yoshida
ORCID
Author(s) ORCID Number
Yuto Aoki http://orcid.org/0000-0002-4361-1325
Youich Kawano http://orcid.org/0000-0002-9177-4305
Junji Ueda http://orcid.org/0000-0001-6189-0762
Tetsuya Shimizu http://orcid.org/0000-0002-5877-9526
Hiroshi Yoshida http://orcid.org/0000-0002-2463-9023
Funding Agency and Grant Number
Funding Agency Grant Number
Designated Scholarship Donations from Otsuka Pharmaceutical Co., Ltd. to the Authors’ Institution (2018-2019)
Corresponding Author Youich Kawano, Associate Professor, MD, PhD, Department of Gastroenterological Surgery, Nippon Medical School, 1-1-5 Sendagi, Tokyo 113-8603, Japan. y-kawano@nms.ac.jp
Key Words Hepatectomy; Liver resection; Vasopressin; Aldosterone; Fluid management; Water retention; Liver surgery
Core Tip This study prospectively assessed postoperative changes in arginine vasopressin (AVP) and plasma aldosterone concentration (PAC) after liver resection and found that AVP elevation persisted longer than PAC elevation, particularly after major resections. The duration of elevated AVP closely matched the period of early postoperative fluid retention, highlighting the important role of AVP beyond the renin-angiotensin-aldosterone system. These findings suggest that targeting the V2 signaling pathway may offer strategies for optimizing fluid management and reducing complications in high-risk patients undergoing liver resection. A detailed understanding of postoperative hormonal changes is crucial for future clinical trials and therapeutic decisions.
Publish Date 2026-03-02 08:37
Citation

Aoki Y, Kawano Y, Ga R, Endo K, Ueda J, Shimizu T, Yoshida H. Vasopressin and fluid retention after liver resection: Comparison with the renin-angiotensin-aldosterone system by surgical extent and liver function. World J Gastroenterol 2026; 32(10): 115167

URL https://www.wjgnet.com/1007-9327/full/v32/i10/115167.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i10.115167
Full Article (PDF) WJG-32-115167-with-cover.pdf
STROBE Statement 115167-STROBE-statement.pdf
Manuscript File 115167_Auto_Edited_073657.docx
Answering Reviewers 115167-answering-reviewers.pdf
Audio Core Tip 115167-audio.mp3
Biostatistics Review Certificate 115167-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 115167-conflict-of-interest-statement.pdf
Copyright License Agreement 115167-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 115167-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 115167-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 115167-non-native-speakers.pdf
Peer-review Report 115167-peer-reviews.pdf
Scientific Misconduct Check 115167-scientific-misconduct-check.png
Scientific Editor Work List 115167-scientific-editor-work-list.pdf
CrossCheck Report 115167-crosscheck-report.pdf