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Publication Name World Journal of Orthopedics
Manuscript ID 115188
Country Nepal
Received
2025-10-14 01:49
Peer-Review Started
2025-10-14 01:49
First Decision by Editorial Office Director
2025-10-27 09:25
Return for Revision
2025-10-27 09:25
Revised
2025-10-28 18:32
Publication Fee Transferred
Second Decision by Editor
2025-11-26 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-26 09:43
Articles in Press
2025-11-26 09:43
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-22 08:52
Publish the Manuscript Online
2026-02-04 06:28
ISSN 2218-5836 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Orthopedics
Manuscript Type Retrospective Cohort Study
Article Title Impact of preoperative frailty on complications, readmissions, and functional recovery following total knee arthroplasty in elderly patients
Manuscript Source Unsolicited Manuscript
All Author List Muhammad Bilal Yasin, Muhammad Raheel, Muhammad Mustafa Ahmed, Sheharyar Ashfaq, Hamdoon Suharwardy Asim, Mohammed Qasim Rauf, Renad Fahim and Rejina Chhetri
ORCID
Author(s) ORCID Number
Rejina Chhetri http://orcid.org/0009-0002-2253-783X
Funding Agency and Grant Number
Corresponding Author Rejina Chhetri, MD, Department of Surgery, Nepalgunj Medical College, Banke Baijanath 1 Chisapani, Kohal 21900, Nepal. rejinachhetri01@gmail.com
Key Words Total knee arthroplasty; Frailty; Modified Frailty Index; Postoperative complications; Elderly; Pakistan; Knee Society Score; Hospital length of stay; Readmission; Functional recovery
Core Tip This retrospective cohort study from Pakistan demonstrates that preoperative frailty, assessed by the modified Frailty Index, significantly increases postoperative complications, hospital length of stay, and 90-day readmissions while impairing 1-year functional recovery in elderly patients undergoing total knee arthroplasty. Findings are most applicable to tertiary referral centers in Pakistan. Routine frailty screening could enhance risk stratification and perioperative management in resource-limited settings, addressing challenges like high tuberculosis prevalence to optimize outcomes and reduce healthcare burdens. A practical pathway includes: (1) The modified Frailty Index ≥ 0.27 to flag high-risk; (2) Initiate low-cost prehabilitation (nutritional screening/supplementation, home-based resistance exercises, medication review); and (3) Multidisciplinary review before surgery.
Publish Date 2026-02-04 06:28
Citation

Yasin MB, Raheel M, Ahmed MM, Ashfaq S, Asim HS, Rauf MQ, Fahim R, Chhetri R. Impact of preoperative frailty on complications, readmissions, and functional recovery following total knee arthroplasty in elderly patients. World J Orthop 2026; 17(2): 115188

URL https://www.wjgnet.com/2218-5836/full/v17/i2/115188.htm
DOI https://dx.doi.org/10.5312/wjo.v17.i2.115188
Full Article (PDF) WJO-17-115188-with-cover.pdf
STROBE Statement 115188-STROBE-statement.pdf
Manuscript File 115188_Auto_Edited_065643.docx
Answering Reviewers 115188-answering-reviewers.pdf
Audio Core Tip 115188-audio.mp3
Biostatistics Review Certificate 115188-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 115188-conflict-of-interest-statement.pdf
Copyright License Agreement 115188-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 115188-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 115188-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 115188-non-native-speakers.pdf
Supplementary Material 115188-supplementary-material.pdf
Peer-review Report 115188-peer-reviews.pdf
Scientific Misconduct Check 115188-scientific-misconduct-check.png
Scientific Editor Work List 115188-scientific-editor-work-list.pdf
CrossCheck Report 115188-crosscheck-report.pdf