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Articles Published Processes
4/20/2026 8:05:34 AM | Browse: 24 | Download: 206
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Received |
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2025-10-31 08:42 |
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Peer-Review Started |
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2025-10-31 08:42 |
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First Decision by Editorial Office Director |
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2025-11-21 06:54 |
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Return for Revision |
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2025-11-21 06:54 |
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Revised |
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2025-12-14 06:04 |
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Publication Fee Transferred |
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2025-12-19 10:10 |
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Second Decision by Editor |
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2026-02-24 02:57 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-02-24 08:13 |
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Articles in Press |
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2026-02-24 08:13 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-04-08 01:07 |
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Publish the Manuscript Online |
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2026-04-20 08:05 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Basic Study |
| Article Title |
WTAP-mediated N6-methyladenosine modification of circ_PVT1 promotes proliferation and tenogenic differentiation of tendon stem/progenitor cells
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yu Chen, Xu Hu, Xiao-Tian Jia, Ren-Zhi Gao, Quan-Shan Hou and Shi-Guo Zhou |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Fujian Province |
2024J011037 |
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| Corresponding Author |
Shi-Guo Zhou, MD, Department of Orthopedics, Shengli Clinical Medical College of Fujian Medical University, Fuzhou University Affiliated Provincial Hospital, No. 134 East Street, Fuzhou 350001, Fujian Province, China. 9201551033@fjmu.edu.cn |
| Key Words |
WTAP; Circular RNA plasmacytoma variant translocation 1; Tenogenic differentiation; Tendon stem/progenitor cells; N6-methyladenosine |
| Core Tip |
Tendon stem/progenitor cells share common characteristics with stem cells, such as proliferation, pluripotency, and self-renewal ability. Under suitable conditions, they can differentiate into tendon cells and play a crucial role in maintaining the stability of tendons and in repair after injury. We found that circular RNA plasmacytoma variant translocation 1 deficiency could inhibit tenogenic differentiation. In addition, WTAP-mediated N6-methyladenosine modification of circular RNA plasmacytoma variant translocation 1 promotes the proliferation and tenogenic differentiation of tendon stem/progenitor cells. These results suggest a promising therapeutic strategy for tendon diseases. |
| Publish Date |
2026-04-20 08:05 |
| Citation |
Chen Y, Hu X, Jia XT, Gao RZ, Hou QS, Zhou SG. WTAP-mediated N6-methyladenosine modification of circ_PVT1 promotes proliferation and tenogenic differentiation of tendon stem/progenitor cells. World J Stem Cells 2026; 18(4): 115218
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| URL |
https://www.wjgnet.com/1948-0210/full/v18/i4/115218.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v18.i4.115218 |
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