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Articles Published Processes
2/6/2026 6:30:40 AM | Browse: 0 | Download: 0
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Received |
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2025-10-15 02:56 |
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Peer-Review Started |
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2025-10-15 02:56 |
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First Decision by Editorial Office Director |
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2025-10-30 08:52 |
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Return for Revision |
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2025-10-30 08:52 |
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Revised |
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2025-11-11 09:47 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-12-25 02:38 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-25 08:41 |
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Articles in Press |
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2025-12-25 08:41 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-01-30 01:01 |
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Publish the Manuscript Online |
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2026-02-06 06:30 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Palpable vs non-palpable breast cancers in screened populations: Clinicopathological features and prognostic implications
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Luca Improta, Gianluca Stanzani, Valeria Vitale, Marco Yusef, Simone Tinghino and Augusto Lombardi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Luca Improta, MD, PhD, Breast Unit, Azienda Ospedaliero-Universitaria Sant’Andrea, Via Di Grottarossa 1035/1039, Rome 00189, Lazio, Italy. luca.dr.improta@gmail.com |
| Key Words |
Breast cancer; Palpable tumor; Tumor aggressiveness; Mammographic screening; Clinicopathological features; Survival outcomes; Ki-67 index; Tumor biology; Prognostic factors; Screening-detected cancer |
| Core Tip |
Despite widespread mammographic screening, many breast cancers still present as palpable masses. This large cohort study (n = 2110) reveals that palpable tumors exhibit aggressive biology-larger size (17.5 mm vs 11.0 mm, P < 0.001), higher grade (G3) (33% vs 16%), elevated Ki-67 (24.7% vs 15.1%), and more frequent luminal B/TN subtypes (P < 0.001). While 10-year survival remained excellent (> 90%) for both groups, palpability served as a clinical marker of rapid tumor growth, underscoring its utility in risk stratification. Findings highlight that even in screened populations, palpable presentation may signal biologically aggressive disease warranting tailored management. |
| Publish Date |
2026-02-06 06:30 |
| Citation |
Improta L, Stanzani G, Vitale V, Yusef M, Tinghino S, Lombardi A. Palpable vs non-palpable breast cancers in screened populations: Clinicopathological features and prognostic implications. World J Clin Oncol 2026; 17(2): 115245 |
| URL |
https://www.wjgnet.com/2218-4333/full/v17/i2/115245.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v17.i2.115245 |
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