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Articles Published Processes
3/6/2026 8:56:58 AM | Browse: 4 | Download: 16
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Received |
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2025-10-14 05:12 |
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Peer-Review Started |
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2025-10-14 05:12 |
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First Decision by Editorial Office Director |
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2025-10-24 11:10 |
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Return for Revision |
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2025-10-24 11:10 |
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Revised |
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2025-10-28 11:55 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-06 02:40 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-06 08:28 |
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Articles in Press |
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2026-01-06 08:28 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-01-29 01:12 |
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Publish the Manuscript Online |
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2026-03-06 08:56 |
| ISSN |
2219-2808 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychology, Clinical |
| Manuscript Type |
Case Control Study |
| Article Title |
Could high serum C-reactive protein levels serve as a biomarker for children and adolescents diagnosed with generalized anxiety disorder
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Kübranur Ünal, Yasemin Taş Torun, Mehmet Emre Erol, Zeynep Kübra Kurt and Cansu Özbaş |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Kübranur Ünal, Associate Professor, MD, Department of Medical Biochemistry, Faculty of Medicine, Gazi University, Emniyet Mahallesi, Bandırma Caddesi, Ankara 06560, Türkiye. kubranurunal@gazi.edu.tr |
| Key Words |
C-reactive protein; Cytokines; Generalized anxiety disorder; Psychiatric; Biomarker; Inflammation |
| Core Tip |
This study investigated the potential relationship between generalized anxiety disorder (GAD) and systemic inflammation in drug-naive children and adolescents. Significantly higher C-reactive protein levels compared to healthy controls suggest a low-grade inflammatory process may be present in pediatric GAD. In contrast, no significant group differences were found in other circulatory immune markers. This selective pattern of elevation suggests that specific components of the inflammatory response may be activated in a limited manner in GAD. Furthermore, the positive correlation between clinical symptom severity and illness duration supports the potential impact of early diagnosis and intervention on symptom progression. However, larger sample sizes and longitudinal studies are needed to more robustly define causal relationships and clinical outcomes. |
| Publish Date |
2026-03-06 08:56 |
| Citation |
Ünal K, Taş Torun Y, Erol ME, Kurt ZK, Özbaş C. Could high serum C-reactive protein levels serve as a biomarker for children and adolescents diagnosed with generalized anxiety disorder. World J Clin Pediatr 2026; 15(1): 115246 |
| URL |
https://www.wjgnet.com/2219-2808/full/v15/i1/115246.htm |
| DOI |
https://dx.doi.org/10.5409/wjcp.v15.i1.115246 |
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