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Articles Published Processes
1/16/2026 11:31:16 AM | Browse: 1 | Download: 0
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Received |
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2025-10-15 02:52 |
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Peer-Review Started |
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2025-10-15 02:52 |
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First Decision by Editorial Office Director |
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2025-11-10 08:01 |
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Return for Revision |
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2025-11-10 08:01 |
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Revised |
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2025-11-19 02:30 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-12-09 02:39 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-10 01:11 |
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Articles in Press |
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2025-12-10 01:11 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-01-13 23:55 |
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Publish the Manuscript Online |
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2026-01-16 11:31 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Observational Study |
| Article Title |
Characteristics of gut microbiota and metabolites in patients with ulcerative colitis with fatigue
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Zi-Xuan Liu, Xiao-Yan Liu, Wei-Wei Tan, Wei-Bing Zhang, Ya-Li Zhang, Lie Zheng and Yan-Cheng Dai |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81873253 |
| National Natural Science Foundation of China |
82574996 |
| the Shanghai Natural Science Foundation |
22ZR1458800 |
| the Scientific Research Project Plan of Shanghai Municipal Health Commission |
202240385 |
| Hongkou District Health Committee |
HKZK2020A01 |
| Shaanxi Province Traditional Chinese Medicine Research and Innovation Talent Plan Project |
TZKN-CXRC-16 |
| Project of Shaanxi Administration of Traditional Chinese Medicine |
SZY-KJCYC-2025-JC-010 |
| Shaanxi Province Key Research and Development Plan Project-Social Development Field |
2025SF-YBXM-498 |
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| Corresponding Author |
Yan-Cheng Dai, Department of Gastroenterology, Shanghai Traditional Chinese Medicine-Integrated Hospital Shanghai University of Traditional Chinese Medicine, No. 230 Baoding Road, Hongkou District, Shanghai 200082, China. daiyancheng2005@126.com |
| Key Words |
Ulcerative colitis; Fatigue; Gut Microbiota; Metabolites; Thromboxane; Anaerococcus |
| Core Tip |
The relationship between disease severity and gut microbes and metabolites in patients with ulcerative colitis (UC) with fatigue remains unclear. To investigate this relationship, we collected fresh stool samples from patients with UC with/without fatigue and healthy individuals with/without fatigue for 16S rRNA sequencing and untargeted metabolomic analysis. Results revealed the gut microbial and metabolomic characteristics of patients with UC with fatigue (HUCF). Patients with HUCF exhibited a distinct gut microbial structure and metabolomic profile. Metabolomic analysis revealed differential expression of metabolites such as linoleoyl ethanolamide, arachidonoyl ethanolamide, glycocholic acid, and thromboxane. Patients with HUCF showed a high relative abundance of Anaerococcus, a beneficial genus. |
| Publish Date |
2026-01-16 11:31 |
| Citation |
Liu ZX, Liu XY, Tan WW, Zhang WB, Zhang YL, Zheng L, Dai YC. Characteristics of gut microbiota and metabolites in patients with ulcerative colitis with fatigue. World J Gastroenterol 2026; 32(3): 115264 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i3/115264.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i3.115264 |
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