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Articles Published Processes
8/5/2026 7:53:13 AM | Browse: 0 | Download: 0
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Received |
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2025-10-15 02:41 |
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Peer-Review Started |
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2025-10-15 03:40 |
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First Decision by Editorial Office Director |
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2025-12-05 09:15 |
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Return for Revision |
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2025-12-05 09:15 |
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Revised |
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2025-12-11 07:36 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-12-29 02:38 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-29 05:37 |
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Articles in Press |
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2025-12-29 05:37 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-07-22 08:46 |
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Publish the Manuscript Online |
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2026-08-05 07:53 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Editorial |
| Article Title |
RRM2 and the ferroptosis-oxidative stress axis in diabetic kidney disease: Emerging insights from recent evidence
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Tong-Jian Zhao and Nian-Zhe Sun |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Nian-Zhe Sun, MD, National Clinical Research Center of Geriatric Disorders, Xiangya Hospital, Central South University, 87 Xiangya Road, Kaifu District, Changsha, Hunan, Changsha 410008, Hunan Province, China. sunnzh201921@sina.com |
| Key Words |
Diabetic kidney disease; Ferroptosis; Oxidative stress; RRM2; PI3K/Akt/Nrf2 signaling; Tubular injury |
| Core Tip |
RRM2 protects against ferroptosis-mediated renal tubular damage by activating the PI3K/Akt/Nrf2 signaling pathway. This discovery deepens our understanding of diabetic kidney disease (DKD) pathogenesis, highlights RRM2 as both a potential biomarker and a therapeutic target. Therefore, strategies for preventing and treating DKD should consider modulating ferroptosis. |
| Publish Date |
2026-08-05 07:53 |
| Citation |
Zhao TJ, Sun NZ. RRM2 and the ferroptosis-oxidative stress axis in diabetic kidney disease: Emerging insights from recent evidence. World J Diabetes 2026; 17(8): 115342
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| URL |
https://www.wjgnet.com/1948-9358/full/v17/i8/115342.htm |
| DOI |
https://doi.org/10.4239/wjd.115342 |
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