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1/19/2026 7:18:25 AM | Browse: 4 | Download: 7
Publication Name World Journal of Hematology
Manuscript ID 115355
Country China
Received
2025-10-16 14:24
Peer-Review Started
2025-10-16 14:24
First Decision by Editorial Office Director
2025-10-22 08:55
Return for Revision
2025-10-22 08:55
Revised
2025-10-24 12:42
Publication Fee Transferred
Second Decision by Editor
2025-12-29 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-29 09:41
Articles in Press
2025-12-29 09:41
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-12 02:40
Publish the Manuscript Online
2026-01-19 07:18
ISSN 2218-6204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Hematology
Manuscript Type Retrospective Study
Article Title Nomogram-based prediction of post-splenectomy thrombocytosis in children with hereditary spherocytosis
Manuscript Source Invited Manuscript
All Author List Tao Zhang, Zhong-Ce Li, Zhu-Bin Pan, Shi-Qin Qi and Ran Tang
ORCID
Author(s) ORCID Number
Ran Tang http://orcid.org/0009-0007-5613-4103
Funding Agency and Grant Number
Funding Agency Grant Number
Anhui Provincial Health and Wellness Scientific Research Project AHWJ2024Aa30300
Corresponding Author Ran Tang, MD, Department of Pediatric Surgery, Anhui Provincial Children’s Hospital, No. 39 Wangjiang East Road, Baohe District, Hefei 231000, Anhui Province, China. njmutr@163.com
Key Words Hereditary spherocytosis; Splenectomy; Thrombocytosis; Risk factors; Nomogram
Core Tip Postoperative thrombocytosis is a frequent complication following splenectomy in children with hereditary spherocytosis, yet its predictors remain unclear. In this large cohort of 230 patients, we identified elevated reticulocyte count, low preoperative platelet count, and higher transfusion volume as independent risk factors. Based on these parameters, we developed and validated a nomogram with excellent discriminative power, good calibration, and strong clinical utility. This practical tool enables early risk stratification and individualized perioperative management, potentially reducing thrombotic complications and improving outcomes in pediatric hereditary spherocytosis patients undergoing splenectomy.
Publish Date 2026-01-19 07:18
Citation

Zhang T, Li ZC, Pan ZB, Qi SQ, Tang R. Nomogram-based prediction of post-splenectomy thrombocytosis in children with hereditary spherocytosis. World J Hematol 2026; 12(1): 115355

URL https://www.wjgnet.com/2218-6204/full/v12/i1/115355.htm
DOI https://dx.doi.org/10.5315/wjh.v12.i1.115355
Full Article (PDF) WJH-12-115355-with-cover.pdf
Manuscript File 115355_Auto_Edited_115045.docx
Answering Reviewers 115355-answering-reviewers.pdf
Audio Core Tip 115355-audio.mp3
Biostatistics Review Certificate 115355-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 115355-conflict-of-interest-statement.pdf
Copyright License Agreement 115355-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 115355-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 115355-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 115355-non-native-speakers.pdf
Peer-review Report 115355-peer-reviews.pdf
Scientific Misconduct Check 115355-scientific-misconduct-check.png
Scientific Editor Work List 115355-scientific-editor-work-list.pdf
CrossCheck Report 115355-crosscheck-report.pdf