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Publication Name World Journal of Psychiatry
Manuscript ID 115373
Country Brazil
Received
2025-10-16 14:27
Peer-Review Started
2025-10-16 14:28
First Decision by Editorial Office Director
2025-11-06 08:43
Return for Revision
2025-11-06 08:43
Revised
2025-11-14 19:16
Publication Fee Transferred
Second Decision by Editor
2025-12-25 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-25 03:33
Articles in Press
2025-12-25 03:33
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-16 09:48
Publish the Manuscript Online
2026-03-30 08:58
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Neurosciences
Manuscript Type Observational Study
Article Title Multidimensional cognitive impairment in hepatosplenic schistosomiasis: A cross-sectional study
Manuscript Source Invited Manuscript
All Author List Iris Campos Lucas, Norma Arteiro Filgueira, Ana Lucia Domingues, Edmundo Pessoa Lopes, Ianca Karine Prudencio Albuquerque and Breno José Alencar Pires Barbosa
ORCID
Author(s) ORCID Number
Iris Campos Lucas http://orcid.org/0000-0001-8394-0062
Norma Arteiro Filgueira http://orcid.org/0000-0002-7549-9825
Ana Lucia Domingues http://orcid.org/0000-0002-1824-7090
Edmundo Pessoa Lopes http://orcid.org/0000-0002-3470-1564
Ianca Karine Prudencio Albuquerque http://orcid.org/0000-0003-2495-4821
Breno José Alencar Pires Barbosa http://orcid.org/0000-0003-4333-2024
Funding Agency and Grant Number
Corresponding Author Iris Campos Lucas, PhD, Professor, Programa de Pós-Graduação em Medicina Tropical, Centro de Ciências Médicas, Universidade Federal de Pernambuco, Av. Prof. Moraes Rego, No. 1235 Cidade Universitária, Recife 50670-901, Pernambuco, Brazil. iriscamposlucas@gmail.com
Key Words Cognitive impairment; Schistosomiasis mansoni; Portal hypertension; Neuropsychological tests; Executive function; Hepatic encephalopathy; Portosystemic shunts; Psychometric; Cross-sectional studies
Core Tip Cognitive impairment in hepatosplenic schistosomiasis goes well beyond minimal hepatic encephalopathy, affecting areas such as visuospatial abilities, working memory, and inhibitory control. Our study, using a brief, culturally adapted assessment battery, found over two-thirds of patients impaired in these domains, often independent of portosystemic shunt presence. These findings call for a paradigm shift from solely minimal hepatic encephalopathy-focused screening to comprehensive, multidimensional cognitive assessment in hepatosplenic schistosomiasis, enabling earlier detection and a more holistic approach to management in endemic, low-resource settings.
Publish Date 2026-03-30 08:58
Citation

Lucas IC, Filgueira NA, Domingues AL, Lopes EP, Albuquerque IKP, Barbosa BJAP. Multidimensional cognitive impairment in hepatosplenic schistosomiasis: A cross-sectional study. World J Psychiatry 2026; 16(4): 115373

URL https://www.wjgnet.com/2220-3206/full/v16/i4/115373.htm
DOI https://dx.doi.org/10.5498/wjp.v16.i4.115373
Full Article (PDF) WJP-16-115373-with-cover.pdf
STROBE Statement 115373-STROBE-statement.pdf
Manuscript File 115373_Auto_Edited_091351.docx
Answering Reviewers 115373-answering-reviewers.pdf
Audio Core Tip 115373-audio.mp3
Biostatistics Review Certificate 115373-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 115373-conflict-of-interest-statement.pdf
Copyright License Agreement 115373-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 115373-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 115373-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 115373-non-native-speakers.pdf
Peer-review Report 115373-peer-reviews.pdf
Scientific Misconduct Check 115373-scientific-misconduct-check.png
Scientific Editor Work List 115373-scientific-editor-work-list.pdf
CrossCheck Report 115373-crosscheck-report.pdf