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3/27/2026 12:16:57 PM | Browse: 1 | Download: 0
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 115383
Country China
Received
2025-10-24 07:39
Peer-Review Started
2025-10-24 07:39
First Decision by Editorial Office Director
2025-11-18 05:18
Return for Revision
2025-11-18 05:18
Revised
2025-11-28 09:56
Publication Fee Transferred
2025-12-02 00:56
Second Decision by Editor
2026-01-12 02:45
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-12 06:27
Articles in Press
2026-01-12 06:27
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-18 02:04
Publish the Manuscript Online
2026-03-27 12:16
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Clinical Trials Study
Article Title Impact of indomethacin combined with pancreatic duct stent placement on high-risk populations of pancreatitis after endoscopic retrograde cholangiopancreatography
Manuscript Source Unsolicited Manuscript
All Author List Kai Xu, Dong-Hai Zhou, Jing-Shan Liu and Jian Feng
ORCID
Author(s) ORCID Number
Kai Xu http://orcid.org/0000-0002-3554-4177
Jian Feng http://orcid.org/0000-0001-7804-5223
Funding Agency and Grant Number
Corresponding Author Kai Xu, MD, PhD, Department of General Surgery, Peking University Shougang Hospital, No. 9 Jinyuangzhuang Road, Beijing 100041, China. xking55555@163.com
Key Words Post-operative pancreatitis; Endoscopic retrograde cholangiopancreatography; Pancreatic duct stent; Indomethacin
Core Tip This study demonstrates that combining indomethacin suppositories with pancreatic duct stent placement significantly reduces postoperative inflammatory markers (interleukin-6, interleukin-10, C-reactive protein) and improves immune function (higher CD4+/CD8+ ratio) in high-risk post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) patients. The dual intervention also shortens pain relief time and hospital stays compared to monotherapy, offering a synergistic strategy to mitigate PEP-related complications. Key findings highlight its superiority in modulating inflammation and enhancing recovery without increasing severe PEP incidence.
Publish Date 2026-03-27 12:16
Citation

Xu K, Zhou DH, Liu JS, Feng J. Impact of indomethacin combined with pancreatic duct stent placement on high-risk populations of pancreatitis after endoscopic retrograde cholangiopancreatography. World J Gastrointest Surg 2026; 18(3): 115383

URL https://www.wjgnet.com/1948-9366/full/v18/i3/115383.htm
DOI https://dx.doi.org/10.4240/wjgs.v18.i3.115383
Full Article (PDF) WJGS-18-115383-with-cover.pdf
CONSORT 2010 Statement 115383-CONSORT-2010-statement.pdf
Manuscript File 115383_Auto_Edited_093403.docx
Answering Reviewers 115383-answering-reviewers.pdf
Audio Core Tip 115383-audio.MP3
Biostatistics Review Certificate 115383-biostatistics-statement.pdf
Clinical Trial Registration Statement 115383-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 115383-conflict-of-interest-statement.pdf
Copyright License Agreement 115383-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 115383-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 115383-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 115383-non-native-speakers.pdf
Peer-review Report 115383-peer-reviews.pdf
Scientific Misconduct Check 115383-scientific-misconduct-check.png
Scientific Editor Work List 115383-scientific-editor-work-list.pdf
CrossCheck Report 115383-crosscheck-report.pdf