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6/24/2026 9:14:09 AM | Browse: 1 | Download: 4
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 115426
Country China
Received
2025-10-17 13:31
Peer-Review Started
2025-10-17 13:31
First Decision by Editorial Office Director
2025-12-04 08:27
Return for Revision
2025-12-04 08:27
Revised
2025-12-07 04:40
Publication Fee Transferred
Second Decision by Editor
2026-01-06 02:48
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-06 06:49
Articles in Press
2026-01-06 06:49
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-06-08 15:56
Publish the Manuscript Online
2026-06-24 09:14
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Opinion Review
Article Title Evolution of Early Fluid Therapy in Acute Pancreatitis: Balancing Perfusion Needs with Fluid Toxicity
Manuscript Source Invited Manuscript
All Author List Xin-Meng Li, Yong-Rui Tao, Jia-Qi Chen and Yuan Chen
ORCID
Author(s) ORCID Number
Yuan Chen http://orcid.org/0009-0000-7163-2070
Funding Agency and Grant Number
Corresponding Author Yuan Chen, MD, . chenyuanx2000@163.com
Key Words Acute pancreatitis; Fluid therapy; Dextran; Ringer’s lactate; Randomized controlled trial; Systemic inflammatory response syndrome; C-reactive protein
Core Tip In early acute pancreatitis, fluid is usually started for the right reason — and continues for the wrong one. The same admission order can run on while the patient has changed underneath it. A patient with persistent hemoconcentration or oliguria still looks under-resuscitated, but a new oxygen requirement, basal crackles, or a tense abdomen should interrupt the next bolus, not justify it. The bedside question shifts from "is perfusion adequate?" to "can this patient still tolerate volume?" — and the answer rarely arrives from a single number. Our argument is simple: reassess early, adjust by tolerance, and resist the inertia of the admission prescription.
Publish Date 2026-06-24 09:14
Citation

Li XM, Tao YR, Chen JQ, Chen Y. Evolution of Early Fluid Therapy in Acute Pancreatitis: Balancing Perfusion Needs with Fluid Toxicity. World J Gastrointest Surg 2026; 18(6): 115426

URL https://www.wjgnet.com/1948-9366/full/v18/i6/115426.htm
DOI https://doi.org/10.4240/wjgs.115426
Full Article (PDF) WJGS-18-115426-with-cover.pdf
Manuscript File 115426_Auto_Edited_082639.docx
Answering Reviewers 115426-answering-reviewers.pdf
Audio Core Tip 115426-audio.m4a
Conflict-of-Interest Disclosure Form 115426-conflict-of-interest-statement.pdf
Copyright License Agreement 115426-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 115426-non-native-speakers.pdf
Peer-review Report 115426-peer-reviews.pdf
Scientific Misconduct Check 115426-scientific-misconduct-check.png
Scientific Editor Work List 115426-scientific-editor-work-list.pdf
CrossCheck Report 115426-crosscheck-report.pdf