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3/27/2026 6:07:06 AM | Browse: 3 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 115440
Country China
Received
2025-10-20 02:00
Peer-Review Started
2025-10-20 02:00
First Decision by Editorial Office Director
2025-11-21 09:59
Return for Revision
2025-11-21 09:59
Revised
2025-12-04 08:37
Publication Fee Transferred
Second Decision by Editor
2026-01-28 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-28 07:41
Articles in Press
2026-01-28 07:41
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-17 05:46
Publish the Manuscript Online
2026-03-27 06:07
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Editorial
Article Title Risk stratification of gastric neuroendocrine tumors in autoimmune gastritis: Evaluating the clinical value of an integrated clinical-endoscopic model
Manuscript Source Invited Manuscript
All Author List Qing-Qing Yu
ORCID
Author(s) ORCID Number
Qing-Qing Yu http://orcid.org/0000-0001-5695-6747
Funding Agency and Grant Number
Corresponding Author Qing-Qing Yu, Professor, Clinical Research Center, Jining No. 1 People's Hospital, No. 6 Jiankang Road, Jining 272000, Shandong Province, China. yuqingqing_lucky@163.com
Key Words Gastric neuroendocrine tumors; Autoimmune gastritis; Integrated model; Endoscope; Integrated model
Core Tip Autoimmune gastritis induces gastric neuroendocrine tumors through a multistep process involving oxyntic mucosal destruction, hypergastrinemia, and enterochromaffin-like cell proliferation. Integrated clinical-endoscopic models utilizing machine learning (e.g., Boruta algorithm) outperform single-parameter approaches, with key predictors including atrophy severity, gastrin levels, and Helicobacter pylori history. These models enable personalized risk-adapted surveillance, inform vitamin B12 chemoprevention, and improve prognostic stratification by incorporating endoscopic and proliferative indices. Current limitations include single-center bias and incomplete molecular integration; future development requires multicenter validation and multimodal biomarkers.
Publish Date 2026-03-27 06:07
Citation

Yu QQ. Risk stratification of gastric neuroendocrine tumors in autoimmune gastritis: Evaluating the clinical value of an integrated clinical-endoscopic model. World J Gastroenterol 2026; 32(13): 115440

URL https://www.wjgnet.com/1007-9327/full/v32/i13/115440.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i13.115440
Full Article (PDF) WJG-32-115440-with-cover.pdf
Manuscript File 115440_Auto_Edited_062425.docx
Answering Reviewers 115440-answering-reviewers.pdf
Audio Core Tip 115440-audio.mp3
Conflict-of-Interest Disclosure Form 115440-conflict-of-interest-statement.pdf
Copyright License Agreement 115440-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 115440-non-native-speakers.pdf
Peer-review Report 115440-peer-reviews.pdf
Scientific Misconduct Check 115440-scientific-misconduct-check.png
Scientific Editor Work List 115440-scientific-editor-work-list.pdf
CrossCheck Report 115440-crosscheck-report.pdf