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1/21/2026 9:49:23 AM | Browse: 1 | Download: 1
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 115444
Country Türkiye
Received
2025-10-20 09:29
Peer-Review Started
2025-10-20 09:29
First Decision by Editorial Office Director
2025-10-31 07:45
Return for Revision
2025-10-31 07:45
Revised
2025-11-05 07:58
Publication Fee Transferred
Second Decision by Editor
2025-11-21 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-21 08:50
Articles in Press
2025-11-21 08:50
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-10 03:47
Publish the Manuscript Online
2026-01-21 09:49
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Prospective Study
Article Title Diagnostic value of interleukin-8 in colon cancer: Prospective, case-control study
Manuscript Source Unsolicited Manuscript
All Author List Gizem Güneş, Esra Fırat Oğuz, Ilgaz Kayılıoğlu and Tolga Dinç
ORCID
Author(s) ORCID Number
Gizem Güneş http://orcid.org/0000-0001-5761-4052
Esra Fırat Oğuz http://orcid.org/0000-0002-8147-5379
Ilgaz Kayılıoğlu http://orcid.org/0000-0002-2933-8983
Tolga Dinç http://orcid.org/0000-0003-3772-7468
Funding Agency and Grant Number
Funding Agency Grant Number
University of Health Sciences No. 2021/144
Corresponding Author Ilgaz Kayılıoğlu, Associate Professor, MD, Department of General Surgery, Izan Private Health Hospital, Ahmetçavuş-Hayıtlı Mah. Atatürk Bul. No. 21, Milas, Muğla 48200, Türkiye. kayilioglu@yahoo.com
Key Words Adenocarcinoma; Biomarkers; Tumor; Colorectal neoplasms; Early detection of cancer; Interleukin-8
Core Tip This prospective study demonstrates that serum interleukin-8 (IL-8) levels were significantly elevated in colon adenocarcinoma patients. Although diagnostic accuracy was moderate (area under the curve = 0.68), IL-8 remained an independent predictor. Prior evidence links IL-8 to survival and treatment response, suggesting diagnostic and prognostic utility. Larger multicenter studies are warranted to confirm and explore therapeutic implications.
Publish Date 2026-01-21 09:49
Citation

Güneş G, Fırat Oğuz E, Kayılıoğlu I, Dinç T. Diagnostic value of interleukin-8 in colon cancer: Prospective, case-control study. World J Gastrointest Surg 2026; 18(1): 115444

URL https://www.wjgnet.com/1948-9366/full/v18/i1/115444.htm
DOI https://dx.doi.org/10.4240/wjgs.v18.i1.115444
Full Article (PDF) WJGS-18-115444-with-cover.pdf
CONSORT 2010 Statement 115444-CONSORT-2010-statement.pdf
Manuscript File 115444_Auto_Edited_065157.docx
Answering Reviewers 115444-answering-reviewers.pdf
Audio Core Tip 115444-audio.wav
Biostatistics Review Certificate 115444-biostatistics-statement.pdf
Clinical Trial Registration Statement 115444-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 115444-conflict-of-interest-statement.pdf
Copyright License Agreement 115444-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 115444-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 115444-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 115444-non-native-speakers.pdf
Peer-review Report 115444-peer-reviews.pdf
Scientific Misconduct Check 115444-scientific-misconduct-check.png
Scientific Editor Work List 115444-scientific-editor-work-list.pdf
CrossCheck Report 115444-crosscheck-report.pdf