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Articles Published Processes
8/17/2026 3:34:31 AM | Browse: 0 | Download: 0
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Received |
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2025-10-17 13:29 |
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Peer-Review Started |
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2025-10-17 13:30 |
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First Decision by Editorial Office Director |
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2025-11-26 07:22 |
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Return for Revision |
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2025-11-26 07:22 |
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Revised |
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2025-11-27 19:32 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-04 02:40 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-04 03:30 |
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Articles in Press |
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2026-01-04 03:30 |
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Edit the Manuscript by Language Editor |
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2026-01-23 00:12 |
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Typeset the Manuscript |
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2026-07-30 08:42 |
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Publish the Manuscript Online |
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2026-08-17 03:34 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Editorial |
| Article Title |
Colloids in acute pancreatitis: Microcirculatory advantage or inflammatory mirage
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Amira Ahmed Abdelrahman Othman |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Amira Ahmed Abdelrahman Othman, Department of Internal Medicine, Suez University, Cairo-Suez Road, Suez 43511, Egypt. amira.othman@med.suezuni.edu.eg |
| Key Words |
Acute pancreatitis; Fluid resuscitation; Colloids; Dextran 40; Ringer’s lactate; Microcirculation; C-reactive protein |
| Core Tip |
Fluid resuscitation remains the cornerstone of acute pancreatitis care; however, the ideal composition remains unsettled. A recent randomized trial comparing dextran 40 + Ringer’s lactate vs Ringer’s lactate alone demonstrated lower C-reactive protein but no difference in systemic inflammation or organ failure. This editorial explores why the apparent biochemical benefit may not translate into clinical improvement, highlighting the intricate interplay between microcirculation, endothelial integrity, and inflammatory signaling. The piece highlights how this study refines, not resolves, the colloid debate, underscoring the need for individualized, goal-directed hydration strategies guided by hemodynamic and perfusion markers rather than fixed formulas. |
| Publish Date |
2026-08-17 03:34 |
| Citation |
Othman AAA. Colloids in acute pancreatitis: Microcirculatory advantage or inflammatory mirage. World J Gastrointest Surg 2026; 18(8): 115464
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| URL |
https://www.wjgnet.com/1948-9366/full/v18/i8/115464.htm |
| DOI |
https://doi.org/10.4240/wjgs.115464 |
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