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4/21/2026 8:57:42 AM | Browse: 4 | Download: 13
Publication Name World Journal of Hepatology
Manuscript ID 115475
Country China
Received
2025-10-31 06:12
Peer-Review Started
2025-10-31 06:12
First Decision by Editorial Office Director
2025-12-03 10:03
Return for Revision
2025-12-03 10:03
Revised
2025-12-15 15:31
Publication Fee Transferred
Second Decision by Editor
2026-01-20 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-20 07:50
Articles in Press
2026-01-20 07:50
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-04-07 06:21
Publish the Manuscript Online
2026-04-21 08:57
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, General & Internal
Manuscript Type Retrospective Study
Article Title Metabolic dysfunction-associated steatotic liver disease mediates the relationship between helicobacter pylori infection and colorectal adenoma risk
Manuscript Source Invited Manuscript
All Author List Zhao-Bei Cai, Bin-Bin Su, Pan-Yang Shi, Sheng-Shu Wang, Hui Shi and Qian-Qian Chen
ORCID
Author(s) ORCID Number
Zhao-Bei Cai http://orcid.org/0000-0002-7785-4018
Hui Shi http://orcid.org/0009-0008-9300-5308
Qian-Qian Chen http://orcid.org/0009-0006-9078-5711
Funding Agency and Grant Number
Corresponding Author Qian-Qian Chen, Associate Chief Physician, Associate Professor, MD, Department of Gastroenterology and Hepatology, The First Medical Center of Chinese PLA General Hospital, No.28 Fuxing Road, Haidian District, Beijing 100853, China. qian_qian_chen@163.com
Key Words Colorectal adenomas; Helicobacter pylori infection; Metabolic dysfunction-associated steatotic liver disease; Interaction; Mediation
Core Tip This study identifies both Helicobacter pylori (H. pylori) infection and metabolic dysfunction-associated steatotic liver disease (MASLD) as independent risk factors for colorectal adenoma. No interaction was found between them, but MASLD mediated the infection-adenoma risk relationship. These results support enhanced screening for colorectal adenoma in individuals with H. pylori infection and MASLD.
Publish Date 2026-04-21 08:57
Citation

Cai ZB, Su BB, Shi PY, Wang SS, Shi H, Chen QQ. Metabolic dysfunction-associated steatotic liver disease mediates the relationship between helicobacter pylori infection and colorectal adenoma risk. World J Hepatol 2026; 18(4): 115475

URL https://www.wjgnet.com/1948-5182/full/v18/i4/115475.htm
DOI https://dx.doi.org/10.4254/wjh.v18.i4.115475
Full Article (PDF) WJH-18-115475-with-cover.pdf
Manuscript File 115475_Auto_Edited_103239.docx
Answering Reviewers 115475-answering-reviewers.pdf
Audio Core Tip 115475-audio.mp3
Biostatistics Review Certificate 115475-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 115475-conflict-of-interest-statement.pdf
Copyright License Agreement 115475-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 115475-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 115475-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 115475-non-native-speakers.pdf
Peer-review Report 115475-peer-reviews.pdf
Scientific Misconduct Check 115475-scientific-misconduct-check.png
Scientific Editor Work List 115475-scientific-editor-work-list.pdf
CrossCheck Report 115475-crosscheck-report.pdf