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Articles Published Processes
3/30/2026 8:58:27 AM | Browse: 37 | Download: 139
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Received |
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2025-11-04 09:00 |
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Peer-Review Started |
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2025-11-04 09:00 |
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First Decision by Editorial Office Director |
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2025-11-26 07:18 |
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Return for Revision |
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2025-11-26 07:18 |
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Revised |
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2025-12-08 15:08 |
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Publication Fee Transferred |
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2025-12-15 08:37 |
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Second Decision by Editor |
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2025-12-26 02:36 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-26 08:58 |
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Articles in Press |
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2025-12-26 08:58 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-03-19 00:42 |
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Publish the Manuscript Online |
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2026-03-30 08:58 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Retrospective Study |
| Article Title |
Correlation analysis of depressive symptoms and immune function indicators in patients with malignant melanoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Shi Dong, Hui-Ling Mou, Hao Zhang and Teng Ye |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Teng Ye, Department of Dermatology and Venereology, The First Affiliated Hospital of Wenzhou Medical University, Shangcai Village, Nanbaixiang, Ouhai District, Wenzhou 325000, Zhejiang Province, China. andy325902@163.com |
| Key Words |
Malignant melanoma; Depressive symptoms; Immune function; Cellular immunity; Inflammatory factors |
| Core Tip |
This retrospective study revealed that over half of malignant melanoma patients experienced depressive symptoms, which were closely associated with suppressed cellular immunity and elevated inflammatory markers such as interleukin-6 (IL-6) and neutrophil-to-lymphocyte ratio. CD4+ T cell count and serum albumin were found to be protective factors, while IL-6 and advanced tumor-node-metastasis stage were risk predictors. A multi-indicator model combining IL-6, CD4+, and neutrophil-to-lymphocyte ratio achieved good predictive performance (area under the curve = 0.834). These findings highlight the need for integrated psychosocial and immunological assessment in melanoma patients to improve mental health and potentially affect prognosis. |
| Publish Date |
2026-03-30 08:58 |
| Citation |
Dong S, Mou HL, Zhang H, Ye T. Correlation analysis of depressive symptoms and immune function indicators in patients with malignant melanoma. World J Psychiatry 2026; 16(4): 115490 |
| URL |
https://www.wjgnet.com/2220-3206/full/v16/i4/115490.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v16.i4.115490 |
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