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Publication Name World Journal of Diabetes
Manuscript ID 115495
Country Bangladesh
Received
2025-10-20 00:20
Peer-Review Started
2025-10-21 08:06
First Decision by Editorial Office Director
2025-11-18 07:48
Return for Revision
2025-11-18 07:48
Revised
2025-11-26 04:17
Publication Fee Transferred
Second Decision by Editor
2025-12-29 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-30 06:13
Articles in Press
2025-12-30 06:13
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-27 06:27
Publish the Manuscript Online
2026-02-06 08:43
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Meta-Analysis
Article Title Safety and efficacy of sodium-glucose cotransporter-2 inhibitors in adults with type 2 diabetes fasting during Ramadan: A meta-analysis
Manuscript Source Invited Manuscript
All Author List Abul Bashar Mohammad Kamrul-Hasan, Shehla Shaikh, Hamid Ashraf, Mohammad Shafi Kuchay, Lakshmi Nagendra, Deep Dutta and Joseph M Pappachan
ORCID
Author(s) ORCID Number
Abul Bashar Mohammad Kamrul-Hasan http://orcid.org/0000-0002-5681-6522
Shehla Shaikh http://orcid.org/0000-0003-4793-5818
Hamid Ashraf http://orcid.org/0000-0001-8002-9142
Mohammad Shafi Kuchay http://orcid.org/0000-0003-3933-6137
Lakshmi Nagendra http://orcid.org/0000-0001-6865-5554
Deep Dutta http://orcid.org/0000-0003-4915-8805
Joseph M Pappachan http://orcid.org/0000-0003-0886-5255
Funding Agency and Grant Number
Corresponding Author Abul Bashar Mohammad Kamrul-Hasan, Assistant Professor, Department of Endocrinology, Mymensingh Medical College, Mymensingh Sadar, Mymensingh 2200, Bangladesh. rangassmc@gmail.com
Key Words Type 2 diabetes; Sodium-glucose cotransporter-2 inhibitors; Ramadan; Religious fasting; Safety; Meta-analysis
Core Tip This meta-analysis assessed the safety and effectiveness of sodium-glucose cotransporter-2 inhibitors (SGLT2i) in adults with type 2 diabetes fasting during Ramadan. Among 12 studies with 3625 participants, SGLT2i increased risks of postural dizziness, hypotension, and sodium loss, but achieved greater reductions in blood pressure and a lower risk of symptomatic hypoglycemia than other glucose-lowering drugs. SGLT2i did not impact glycemic control, body weight, or renal function. Other adverse events, like dehydration and severe hypoglycemia, showed no significant difference. SGLT2i appear safe and effective for diabetes management during Ramadan fasting, but larger studies are needed to confirm safety for vulnerable groups.
Publish Date 2026-02-06 08:43
Citation

Kamrul-Hasan ABM, Shaikh S, Ashraf H, Kuchay MS, Nagendra L, Dutta D, Pappachan JM. Safety and efficacy of sodium-glucose cotransporter-2 inhibitors in adults with type 2 diabetes fasting during Ramadan: A meta-analysis. World J Diabetes 2026; 17(2): 115495

URL https://www.wjgnet.com/1948-9358/full/v17/i2/115495.htm
DOI https://dx.doi.org/10.4239/wjd.v17.i2.115495
Full Article (PDF) WJD-17-115495-with-cover.pdf
PRISMA 2009 Checklist 115495-PRISMA-2009-Checklist.pdf
Manuscript File 115495_Auto_Edited_072647.docx
Answering Reviewers 115495-answering-reviewers.pdf
Audio Core Tip 115495-audio.m4a
Biostatistics Review Certificate 115495-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 115495-conflict-of-interest-statement.pdf
Copyright License Agreement 115495-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 115495-non-native-speakers.pdf
Supplementary Material 115495-supplementary-material.pdf
Peer-review Report 115495-peer-reviews.pdf
Journal Editor-in-Chief Review Report 115495-journal-editor-in-chief.pdf
Scientific Misconduct Check 115495-scientific-misconduct-check.png
Scientific Editor Work List 115495-scientific-editor-work-list.pdf
CrossCheck Report 115495-crosscheck-report.pdf