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Articles Published Processes
5/26/2026 3:52:09 AM | Browse: 0 | Download: 0
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Received |
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2025-10-20 01:52 |
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Peer-Review Started |
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2025-10-20 01:52 |
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First Decision by Editorial Office Director |
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2025-11-24 12:53 |
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Return for Revision |
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2025-11-24 15:47 |
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Revised |
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2025-12-02 12:08 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-06 02:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-07 01:00 |
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Articles in Press |
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2026-01-07 01:00 |
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Edit the Manuscript by Language Editor |
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2026-01-23 00:09 |
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Typeset the Manuscript |
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2026-05-12 01:17 |
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Publish the Manuscript Online |
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2026-05-26 03:52 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Correspondence |
| Article Title |
Letter to the Editor: Gut microbiota–bile acid crosstalk - prevotellaceae NK3B31 and 7-ketolithocholic acid drive metabolic benefits of distal bowel resection with preservation of terminal ileum
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Xu Cui, Long-Yao Xu, Bing-Qian Yin, Liu Chen, Zheng Liang and Chao-Ming Zhou |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Fujian Provincial Science and Technology Innovation Joint Fund Project |
No.2024Y9555 |
| Fujian Provincial Natural Science Foundation Project |
No.2025J01226 |
| Fuian Provincial Medical Project for Creating Dual High-Ouality Development (High Level and High Standard) |
No.ETK2025004 |
| Fujian Medical University Qihang Fund |
No.2023QH1239 |
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| Corresponding Author |
Chao-Ming Zhou, Department of Pediatric Surgery, Fujian Children’s Hospital (Fujian Branch of Shanghai Children’s Medical Center), College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, No. 966 Hengyu Road, Fuzhou 350001, Fujian Province, China. fjsetyyzcm@163.com |
| Key Words |
Distal bowel resection with terminal ileum preservation; Gut microbiota; Bile acid metabolism; Prevotellaceae NK3B31 group; 7-ketolithocholic acid; Glucose homeostasis |
| Core Tip |
Xu et al revealed that the Prevotellaceae NK3B31 group/7-ketolithocholic acid (7-KLCA)/farnesoid X receptor (FXR) axis drives hepatic gluconeogenesis suppression in distal bowel resection with terminal ileum preservation; a metabolic surgery model. Multiomics linked microbial enrichment to 7-KLCA elevation and FXR activation, downregulating gluconeogenic genes. This improves understanding of gut microbiota–bile acid crosstalk, highlighting species-specific bile acid roles. Translational potential lies in targeting this axis (probiotics/7-KLCA analogs) for metabolic disease. |
| Publish Date |
2026-05-26 03:52 |
| Citation |
Cui X, Xu LY, Yin BQ, Chen L, Liang Z, Zhou CM. Letter to the Editor: Gut microbiota–bile acid crosstalk - prevotellaceae NK3B31 and 7-ketolithocholic acid drive metabolic benefits of distal bowel resection with preservation of terminal ileum. World J Hepatol 2026; 18(5): 115514 |
| URL |
https://www.wjgnet.com/1948-5182/full/v18/i5/115514.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v18.i5.115514 |
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