BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
1/16/2026 11:31:18 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 115527
Country China
Received
2025-10-21 02:13
Peer-Review Started
2025-10-21 02:13
First Decision by Editorial Office Director
2025-10-30 09:36
Return for Revision
2025-10-30 09:36
Revised
2025-11-10 03:04
Publication Fee Transferred
2025-11-11 14:40
Second Decision by Editor
2025-12-16 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-16 08:04
Articles in Press
2025-12-16 08:04
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-09 03:28
Publish the Manuscript Online
2026-01-16 11:31
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Application of machine learning models in predicting the risk of thromboembolic events in patients with nonvariceal gastrointestinal bleeding
Manuscript Source Unsolicited Manuscript
All Author List Chao Lu, Hao-Yang Cheng, Ren-Ke Zhu, Yi-De Zhou, Ke-Fang Sun, Lei Xu, Jian-Zhong Sang, Jiao-E Chen, Chao-Hui Yu, Yu-Lu Qin and Lan Li
ORCID
Author(s) ORCID Number
Lei Xu http://orcid.org/0000-0001-6017-3745
Chao-Hui Yu http://orcid.org/0000-0003-4842-3646
Lan Li http://orcid.org/0000-0001-8401-4001
Funding Agency and Grant Number
Corresponding Author Lan Li, Chief Physician, Department of Gastroenterology, The First Affiliated Hospital, Zhejiang University, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. nalil@zju.edu.cn
Key Words Nonvariceal gastrointestinal bleeding; Thromboembolic event; Machine learning; Categorical boosting; D-dimer
Core Tip This multicenter study developed and validated five machine learning models to predict thromboembolic risk in patients with nonvariceal gastrointestinal bleeding. Using ten key clinical variables identified by categorical boosting and SHapley Additive exPlanations analysis, all models showed superior predictive performance to D-dimer alone, with the categorical boosting model achieving the best calibration and accuracy. These models can help clinicians identify high-risk patients for early intervention while reducing unnecessary monitoring in low-risk individuals.
Publish Date 2026-01-16 11:31
Citation

Lu C, Cheng HY, Zhu RK, Zhou YD, Sun KF, Xu L, Sang JZ, Chen JE, Yu CH, Qin YL, Li L. Application of machine learning models in predicting the risk of thromboembolic events in patients with nonvariceal gastrointestinal bleeding. World J Gastroenterol 2026; 32(3): 115527

URL https://www.wjgnet.com/1007-9327/full/v32/i3/115527.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i3.115527
Full Article (PDF) WJG-32-115527-with-cover.pdf
STROBE Statement 115527-STROBE-statement.pdf
Manuscript File 115527_Auto_Edited_062727.docx
Answering Reviewers 115527-answering-reviewers.pdf
Audio Core Tip 115527-audio.mp3
Biostatistics Review Certificate 115527-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 115527-conflict-of-interest-statement.pdf
Copyright License Agreement 115527-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 115527-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 115527-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 115527-non-native-speakers.pdf
Supplementary Material 115527-supplementary-material.pdf
Peer-review Report 115527-peer-reviews.pdf
Scientific Misconduct Check 115527-scientific-misconduct-check.png
Scientific Editor Work List 115527-scientific-editor-work-list.pdf
CrossCheck Report 115527-crosscheck-report.pdf