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Publication Name World Journal of Cardiology
Manuscript ID 115528
Country Kyrgyzstan
Received
2025-10-20 10:18
Peer-Review Started
2025-10-20 10:19
First Decision by Editorial Office Director
2025-10-30 09:15
Return for Revision
2025-10-30 09:15
Revised
2025-11-01 09:52
Publication Fee Transferred
Second Decision by Editor
2025-12-17 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-17 08:51
Articles in Press
2025-12-17 08:51
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-02 07:48
Publish the Manuscript Online
2026-02-09 07:31
ISSN 1949-8462 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Retrospective Cohort Study
Article Title Efficacy of nitroglycerin vs labetalol in hypertensive emergency among patients with a history of coronary artery disease
Manuscript Source Unsolicited Manuscript
All Author List Ahmed Jamal Chaudhary, Wasim Akbar Bhat, Affan Ul Haq, Haroon Ur Rashid, Irum Dad Khan, Mah Noor Dad Khan, Hafiz Muhammad Mubeen Nawaz, Sameer Ali and Muhammad Hamza Tariq
ORCID
Author(s) ORCID Number
Ahmed Jamal Chaudhary http://orcid.org/0000-0001-6126-4139
Wasim Akbar Bhat http://orcid.org/0000-0003-3963-9736
Affan Ul Haq http://orcid.org/0009-0009-5387-512X
Haroon Ur Rashid http://orcid.org/0000-0001-6651-2736
Irum Dad Khan http://orcid.org/0000-0001-5306-6300
Mah Noor Dad Khan http://orcid.org/0009-0003-0130-9800
Hafiz Muhammad Mubeen Nawaz http://orcid.org/0000-0003-1716-9999
Sameer Ali http://orcid.org/0000-0002-1738-5280
Muhammad Hamza Tariq http://orcid.org/0009-0003-4863-5443
Funding Agency and Grant Number
Corresponding Author Muhammad Hamza Tariq, MD, Department of Cardiology, International Medical University, Ankara Street 1/17, Bishkek 720052, Kyrgyzstan. muhammadhamzatariq103@gmail.com
Key Words Hypertensive emergency; Coronary artery disease; Nitroglycerin; Labetalol; Blood pressure control; Cardiovascular outcomes
Core Tip This retrospective study uniquely compares intravenous nitroglycerin and labetalol for managing hypertensive emergencies in a large South Asian cohort of patients with established coronary artery disease. Although labetalol achieved target blood pressure more rapidly, nitroglycerin provided greater magnitude of blood pressure reduction, significantly lower rates of bradycardia, smaller rises in cardiac biomarkers, shorter intensive care unit and hospital stays, and reduced 30-day readmissions. These findings highlight nitroglycerin’s potential advantages in ischemic contexts and support its preferential use in high-risk coronary artery disease patients within resource-constrained settings.
Publish Date 2026-02-09 07:31
Citation

Chaudhary AJ, Bhat WA, Ul Haq A, Rashid HU, Khan ID, Khan MND, Nawaz HMM, Ali S, Tariq MH. Efficacy of nitroglycerin vs labetalol in hypertensive emergency among patients with a history of coronary artery disease. World J Cardiol 2026; 18(2): 115528

URL https://www.wjgnet.com/1949-8462/full/v18/i2/115528.htm
DOI https://dx.doi.org/10.4330/wjc.v18.i2.115528
Full Article (PDF) WJC-18-115528-with-cover.pdf
STROBE Statement 115528-STROBE-statement.pdf
Manuscript File 115528_Auto_Edited_114714.docx
Answering Reviewers 115528-answering-reviewers.pdf
Audio Core Tip 115528-audio.mp3
Biostatistics Review Certificate 115528-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 115528-conflict-of-interest-statement.pdf
Copyright License Agreement 115528-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 115528-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 115528-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 115528-non-native-speakers.pdf
Peer-review Report 115528-peer-reviews.pdf
Scientific Misconduct Check 115528-scientific-misconduct-check.png
Scientific Editor Work List 115528-scientific-editor-work-list.pdf
CrossCheck Report 115528-crosscheck-report.pdf