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Articles Published Processes
1/20/2015 9:10:00 PM | Browse: 1067 | Download: 1470
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Received |
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2014-05-27 19:54 |
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Peer-Review Started |
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2014-05-27 21:08 |
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To Make the First Decision |
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2014-06-27 17:43 |
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Return for Revision |
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2014-07-03 10:15 |
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Revised |
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2014-07-22 10:42 |
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Second Decision |
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2014-09-05 16:40 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-09-05 17:12 |
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Articles in Press |
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2014-09-05 17:25 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2014-09-20 03:53 |
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Typeset the Manuscript |
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2015-01-04 19:12 |
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Publish the Manuscript Online |
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2015-01-20 20:12 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Virology |
| Manuscript Type |
Autobiography |
| Article Title |
Experimental infection of Z:ZCLA mongolian gerbils with human hepatitis E virus
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yan Hong, Zhuo-Jing He, Wei Tao, Ting Fu, Yan-Kun Wang and Yong Chen |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Science Technology Department of Zhejiang Province |
2011F20015 |
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| Corresponding Author |
Yan Hong, Professor, Institute of Bioengineering, Zhejiang Academy of Medical Science, 182 Tianmushan Road, Xihu District, Hangzhou 310013, Zhejiang Province, China. hongy1008@163.com |
| Key Words |
Hepatitis E virus; Mongolian gerbils; Infection; Interspecies transmission; Zoonosis |
| Core Tip |
Z:ZCLA Mongolian gerbils were infected with human hepatitis E virus (HEV). Feces samples from gerbils were collected weekly for reverse transcription nested polymerase chain reaction. Serum anti-HEV IgG and alanine aminotransferase (ALT) detection was carried out by enzyme linked immunosorbent assay. At sacrifice, animal liver, spleen, and kidney were collected for histopathologic examination. HEV RNA was detected in fecal samples 7 d after inoculation, and lasted for 42 d. Interestingly, ALT levels were moderately increased in infected animals compared with the control group. These findings indicated that Z:ZCLA Mongolian gerbils are susceptible to human HEV. |
| Publish Date |
2015-01-20 20:12 |
| Citation |
Hong Y, He ZJ, Tao W, Fu T, Wang YK, Chen Y. Experimental infection of Z:ZCLA Mongolian gerbils with human hepatitis E virus. World J Gastroenterol 2015; 21(3): 862-867 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i3/862.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i3.862 |
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