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Articles Published Processes
12/26/2025 10:27:31 AM | Browse: 89 | Download: 226
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Received |
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2025-10-20 02:03 |
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Peer-Review Started |
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2025-10-20 02:03 |
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First Decision by Editorial Office Director |
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2025-10-23 08:23 |
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Return for Revision |
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2025-10-23 08:23 |
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Revised |
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2025-10-27 14:12 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-11-24 02:45 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-11-24 06:32 |
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Articles in Press |
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2025-11-24 06:32 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-12-18 02:20 |
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Publish the Manuscript Online |
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2025-12-26 10:27 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Letter to the Editor |
| Article Title |
Ultrasound imaging in orthotopic hepatocellular carcinoma models: Promise, practicality, and points for refinement
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Devlina Ghosh and Alok Kumar |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Devlina Ghosh, Assistant Professor, PhD, Department of Biochemistry, Saraswati Dental College and Hospital, 233 Tiwariganj, Ayodhya Road, Lucknow 226028, Uttar Pradesh, India. ghoshdevlin6@gmail.com |
| Key Words |
Hepatocellular carcinoma; Ultrasound imaging; Histology; Tumor growth monitoring; Tumor volumetry |
| Core Tip |
High frequency ultrasound is a rapid, low-cost, minimally invasive tool for serial volumetric monitoring of orthotopic hepatocellular carcinoma that correlates well with terminal histology and can match micro computed tomography (CT)/magnetic resonance imaging (MRI) for gross tumor size, but it lacks cellular resolution and remains operator-dependent. To increase translational impact, future work should standardize acquisition and training, perform multimodal validation in subset cohorts (histology, micro CT/MRI), and adopt contrast-enhanced/photoacoustic imaging, along with automated radiomics/artificial intelligence segmentation to reduce bias and improve sensitivity. |
| Publish Date |
2025-12-26 10:27 |
| Citation |
Ghosh D, Kumar A. Ultrasound imaging in orthotopic hepatocellular carcinoma models: Promise, practicality, and points for refinement. World J Hepatol 2025; 17(12): 115551 |
| URL |
https://www.wjgnet.com/1948-5182/full/v17/i12/115551.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v17.i12.115551 |
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