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Articles Published Processes
5/11/2026 9:00:18 AM | Browse: 7 | Download: 23
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Received |
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2025-10-24 00:47 |
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Peer-Review Started |
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2025-10-24 09:12 |
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First Decision by Editorial Office Director |
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2025-11-25 07:49 |
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Return for Revision |
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2025-11-25 07:49 |
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Revised |
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2025-12-17 08:35 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-02-06 02:46 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-02-06 04:00 |
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Articles in Press |
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2026-02-06 04:00 |
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Edit the Manuscript by Language Editor |
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2026-02-10 01:12 |
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Typeset the Manuscript |
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2026-04-28 10:54 |
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Publish the Manuscript Online |
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2026-05-11 09:00 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Public, Environmental & Occupational Health |
| Manuscript Type |
Minireviews |
| Article Title |
Dual effects of synthetic phenolic antioxidants in type 2 diabetes mellitus: Mechanisms and advances
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Xin Li, Peng-Cheng Yuan, Qian Gao, Qing-Qing Cao, Zhen Ma, Xuan Chen, Chong-Jian Wang, Zhen-Xing Mao and Wen-Qian Huo |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
No. 21806146 |
| Postdoctoral Science Foundation of China |
No. 2021M702934 |
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| Corresponding Author |
Wen-Qian Huo, Associate Professor, PhD, Department of Occupational and Environmental Health, College of Public Health, Zhengzhou University, No. 100 Kexue Avenue, Zhengzhou 450001, Henan Province, China. huowenqian@zzu.edu.cn |
| Key Words |
Synthetic phenolic antioxidants; Type 2 diabetes mellitus; Dual effects; Butylated hydroxyanisole; Butylated hydroxytoluene; Tert-butylhydroquinone |
| Core Tip |
This review is the first to systematically elucidate the dual regulatory role of synthetic phenolic antioxidants in the development of type 2 diabetes mellitus, identifying the balance of the nuclear factor erythroid 2-related factor 2/nuclear factor kappa-light-chain-enhancer of activated B cells pathway as the core regulatory mechanism. However, it must be acknowledged that current evidence predominantly comes from preclinical studies, making it difficult to extrapolate the findings to human populations. |
| Publish Date |
2026-05-11 09:00 |
| Citation |
Li X, Yuan PC, Gao Q, Cao QQ, Ma Z, Chen X, Wang CJ, Mao ZX, Huo WQ. Dual effects of synthetic phenolic antioxidants in type 2 diabetes mellitus: Mechanisms and advances. World J Diabetes 2026; 17(5): 115619 |
| URL |
https://www.wjgnet.com/1948-9358/full/v17/i5/115619.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v17.i5.115619 |
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