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4/8/2026 7:28:53 AM | Browse: 0 | Download: 0
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 115635
Country China
Received
2025-10-22 09:47
Peer-Review Started
2025-10-22 09:49
First Decision by Editorial Office Director
2025-11-19 10:44
Return for Revision
2025-11-20 13:54
Revised
2025-12-04 12:32
Publication Fee Transferred
2025-12-09 10:27
Second Decision by Editor
2026-02-04 02:52
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-04 06:59
Articles in Press
2026-02-04 06:59
Edit the Manuscript by Language Editor
2026-02-10 10:45
Typeset the Manuscript
2026-03-27 00:54
Publish the Manuscript Online
2026-04-08 07:28
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Deep learning radiomics nomogram based on multi-regional features for predicting lymph node metastasis and prognosis in colorectal cancer
Manuscript Source Unsolicited Manuscript
All Author List Xue-Di Lei, Gui-Xiang Qian, Zhi-Gang Sun, Zi-Qi Tang, Yuan-Cheng Liu, Rui Du and Yong-Hai Li
ORCID
Author(s) ORCID Number
Xue-Di Lei http://orcid.org/0009-0006-6197-4644
Gui-Xiang Qian http://orcid.org/0000-0002-3971-7258
Zhi-Gang Sun http://orcid.org/0009-0000-9466-4817
Zi-Qi Tang http://orcid.org/0009-0000-1216-449X
Yuan-Cheng Liu http://orcid.org/0009-0008-4252-8619
Rui Du http://orcid.org/0000-0002-8224-0619
Yong-Hai Li http://orcid.org/0009-0008-9643-9515
Funding Agency and Grant Number
Funding Agency Grant Number
Anhui Provincial Research Project on the Inheritance and Innovation of Traditional Chinese Medicine No. 2024CCCX007
Graduate Research and Innovation Program of Bengbu Medical University No. Byycxz24046
Corresponding Author Yong-Hai Li, MD, Department of Anorectal Surgery, The First People’s Hospital of Hefei, No. 390 Huaihe Road, Hefei 230001, Anhui Province, China. liyonghai@ahmu.edu.cn
Key Words Colorectal cancer; Radiomics; Deep learning; Lymph node metastasis; Prognosis; Contrast-enhanced computed tomography; Nomogram; Shapley additive explanation
Core Tip Accurate preoperative prediction of lymph node metastasis is crucial for optimizing treatment strategies in colorectal cancer. In this study, we developed an interpretable clinical-deep learning-radiomics nomogram (DLRN) by integrating clinical features with multi-regional radiomics and deep learning features. Moreover, the DLRN-based prognostic model effectively predicted 3-year recurrence-free survival. As a noninvasive preoperative tool, the DLRN demonstrated strong predictive accuracy for lymph node metastasis in colorectal cancer and offers a practical means for individualized risk stratification and informed treatment decision-making.
Publish Date 2026-04-08 07:28
Citation

Lei XD, Qian GX, Sun ZG, Tang ZQ, Liu YC, Du R, Li YH. Deep learning radiomics nomogram based on multi-regional features for predicting lymph node metastasis and prognosis in colorectal cancer. World J Gastrointest Oncol 2026; 18(4): 115635

URL https://www.wjgnet.com/1948-5204/full/v18/i4/115635.htm
DOI https://dx.doi.org/10.4251/wjgo.v18.i4.115635
Full Article (PDF) WJGO-18-115635-with-cover.pdf
STROBE Statement 115635-STROBE-statement.pdf
Manuscript File 115635_Auto_Edited_024504.docx
Answering Reviewers 115635-answering-reviewers.pdf
Audio Core Tip 115635-audio.mp3
Biostatistics Review Certificate 115635-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 115635-conflict-of-interest-statement.pdf
Copyright License Agreement 115635-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 115635-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 115635-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 115635-non-native-speakers.pdf
Peer-review Report 115635-peer-reviews.pdf
Scientific Misconduct Check 115635-scientific-misconduct-check.png
Scientific Editor Work List 115635-scientific-editor-work-list.pdf
CrossCheck Report 115635-crosscheck-report.pdf