| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Lean type 2 diabetes mellitus is an independent predictor of mortality in primary biliary cholangitis
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ting-Ting Yin, Hui-Ying Lin, Min Zhou, Jian-Wei Li, Qiu-Lan Mo, Hong-Jing Wang, Jie Chen, Hui-Ling Zhu, Yu-Ting Li, Meng-Yao Zheng and Jin-Hui Yang |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
82160106 |
| Yunnan Provincial Department of Education Scientific Research Fund Project |
2025J0270 |
| Yunnan Provincial Science and Technology Department Science and Technology Program Project |
202501AY070001-088 |
|
| Corresponding Author |
Jin-Hui Yang, Chief Physician, Full Professor, Department of Gastroenterology, The Second Affiliated Hospital of Kunming Medical University, No. 374 Dianmian Avenue, Wuhua District, Kunming 650101, Yunnan Province, China. yangjinhui@kmmu.edu.cn |
| Key Words |
Diabetes mellitus; Lean body weight; Nutritional status; Primary biliary cholangitis; Prognosis |
| Core Tip |
Although the adverse prognostic implications of lean diabetes have been documented in various disease contexts, its specific impact on clinical outcomes and underlying mechanisms in primary biliary cholangitis patients remain largely unexplored. This study represents the first comprehensive investigation that systematically evaluates the detrimental effects of lean diabetes on primary biliary cholangitis patient prognosis and critically examines the synergistic interaction and cooperative enhancement mechanisms between diabetes and lean phenotype. |
| Publish Date |
2026-03-27 06:07 |
| Citation |
Yin TT, Lin HY, Zhou M, Li JW, Mo QL, Wang HJ, Chen J, Zhu HL, Li YT, Zheng MY, Yang JH. Lean type 2 diabetes mellitus is an independent predictor of mortality in primary biliary cholangitis. World J Gastroenterol 2026; 32(13): 115649 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i13/115649.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i13.115649 |