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5/26/2026 3:52:09 AM | Browse: 0 | Download: 0
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Received |
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2025-10-24 05:15 |
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Peer-Review Started |
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2025-10-24 05:15 |
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First Decision by Editorial Office Director |
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2025-11-18 10:59 |
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Return for Revision |
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2025-11-18 11:08 |
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Revised |
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2025-12-01 07:41 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-02-04 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-02-04 06:20 |
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Articles in Press |
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2026-02-04 06:20 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-05-14 04:59 |
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Publish the Manuscript Online |
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2026-05-26 03:52 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Kaempferol attenuates diet-induced obesity and hepatic steatosis in C57BL/6J mice fed an Indian diet-mimicking regimen
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Bhagyalakshmi Nair, Rajesh Gopalakrishna and Lekshmi R Nath |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Amrita Vishwa Vidyapeetham Seed Grant |
K-PHAR-22-662 |
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| Corresponding Author |
Lekshmi R Nath, Associate Professor, PhD, Department of Pharmacognosy, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Science Campus, Ponekkara PO, Kochi 682041, Kerala, India. lekshmirnath@aims.amrita.edu |
| Key Words |
Metabolic dysfunction-associated steatotic liver disease; Indian high fat diet; High calorie diet; Natural product; Kaempferol; Hepatic steatosis |
| Core Tip |
Metabolic dysfunction-associated steatotic liver disease spans from simple fat accumulation to cirrhosis and liver cancer, and its prevalence is steadily rising in India due to high fat, high sugar dietary habits. Kaempferol, a generally recognized as safe-approved flavonoid lipid-lowering effects, shows therapeutic potential but has not yet been evaluated in Indian diet-specific obesity driven liver disease models. This study demonstrates that kaempferol effectively attenuates diet-induced obesity and liver steatosis in C57BL/6J mice fed an Indian diet-mimicking regimen. The findings highlight kaempferol’s potential as a natural therapeutic agent for managing metabolic dysfunction and fatty liver disease associated with high calorie, region-specific dietary patterns. |
| Publish Date |
2026-05-26 03:52 |
| Citation |
Nair B, Gopalakrishna R, Nath LR. Kaempferol attenuates diet-induced obesity and hepatic steatosis in C57BL/6J mice fed an Indian diet-mimicking regimen. World J Hepatol 2026; 18(5): 115659 |
| URL |
https://www.wjgnet.com/1948-5182/full/v18/i5/115659.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v18.i5.115659 |
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