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3/12/2026 12:25:37 PM | Browse: 3 | Download: 9
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 115664
Country China
Received
2025-10-22 08:57
Peer-Review Started
2025-10-22 08:57
First Decision by Editorial Office Director
2025-11-14 09:23
Return for Revision
2025-11-17 13:00
Revised
2025-12-01 07:49
Publication Fee Transferred
2025-12-04 14:22
Second Decision by Editor
2025-12-30 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-30 08:53
Articles in Press
2025-12-30 08:53
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-06 08:23
Publish the Manuscript Online
2026-03-12 12:25
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Retrospective Cohort Study
Article Title Preoperative circulating tumor cells as a prognostic indicator in gastric cancer
Manuscript Source Unsolicited Manuscript
All Author List Qiu-Xian Chen, Wei-Ming Zeng, Yong-Bin Zhang, Yi-Chen Cai, Chen-Bin Lv, Yu-Qin Sun and Li-Sheng Cai
ORCID
Author(s) ORCID Number
Qiu-Xian Chen http://orcid.org/0000-0003-0166-969X
Li-Sheng Cai http://orcid.org/0009-0003-6720-9896
Funding Agency and Grant Number
Funding Agency Grant Number
Natural Science Foundation of Fujian Province 2024J011567
Corresponding Author Li-Sheng Cai, Adjunct Associate Professor, Chief Physician, Department of Gastric and Small Bowel Surgery, Zhangzhou Affiliated Hospital of Fujian Medical University, No. 59 West Shengli Road, Zhangzhou 363000, Fujian Province, China. wxccls2024@163.com
Key Words Gastric cancer; Circulating tumor cells; Clinicopathological characteristics; Survival; Risk stratification
Core Tip This study demonstrates that preoperative detection of circulating tumor cells (CTCs) is a potent and minimally invasive prognostic tool for gastric cancer. We found that CTCs-positive status was significantly associated with aggressive clinicopathological features, including advanced tumor stage and metastasis. Importantly, CTCs positivity was an independent predictor of significantly shorter progression-free survival. These findings strongly support the integration of preoperative CTCs testing into standard clinical practice to enhance risk stratification and guide personalized treatment decisions for patients with gastric cancer.
Publish Date 2026-03-12 12:25
Citation

Chen QX, Zeng WM, Zhang YB, Cai YC, Lv CB, Sun YQ, Cai LS. Preoperative circulating tumor cells as a prognostic indicator in gastric cancer. World J Gastrointest Oncol 2026; 18(3): 115664

URL https://www.wjgnet.com/1948-5204/full/v18/i3/115664.htm
DOI https://dx.doi.org/10.4251/wjgo.v18.i3.115664
Full Article (PDF) WJGO-18-115664-with-cover.pdf
STROBE Statement 115664-STROBE-statement.pdf
Manuscript File 115664_Auto_Edited_085421.docx
Answering Reviewers 115664-answering-reviewers.pdf
Audio Core Tip 115664-audio.mp3
Biostatistics Review Certificate 115664-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 115664-conflict-of-interest-statement.pdf
Copyright License Agreement 115664-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 115664-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 115664-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 115664-non-native-speakers.pdf
Peer-review Report 115664-peer-reviews.pdf
Scientific Misconduct Check 115664-scientific-misconduct-check.png
Scientific Editor Work List 115664-scientific-editor-work-list.pdf
CrossCheck Report 115664-crosscheck-report.pdf