| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Psychological and hematological factors associated with fatigue in patients with Crohn’s disease receiving pharmacological treatment
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Tayane C Morais, Genalva Couto, Bruno César da Silva, Raísa A Lisbôa, Bruna S da Cruz, Maria G F Viana, Gabriela B C de Sousa, Lara P Arenas, Erick S Nery, Flora Maria Lorenzo Fortes, Neogélia Pereira de Almeida, Andréa Maia Pimentel, Jaciane Araújo Mota Fontes, Valdiana Cristina Surlo, Julio Fonseca Chebli, Raquel Rocha and Genoile Oliveira Santana |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Raquel Rocha, School of Nutrition, Federal University of Bahia, Rua Augusto Viana, Campus Universitário Canela, Salvador 40170-110, Bahia, Brazil. raquelrocha@ufba.br |
| Key Words |
Inflammatory bowel disease; Crohn’s disease; Fatigue; Anemia; Immune system; Insomnia; Leukocyte profile |
| Core Tip |
Fatigue is one of the most common and challenging symptoms reported by adults with inflammatory bowel disease. We evaluated the association between fatigue and sociodemographic profile, depression, anxiety, stress, insomnia, iron deficiency, vitamin B1 and B12 deficiencies, thyroid function, anemia, leukocyte count, and sedentary lifestyle in patients with Crohn’s disease. An association was found with the following variables: Sedentary lifestyle, shorter time since CD diagnosis, combination of depression, anxiety, stress and insomnia, total leukocyte and segmented neutrophil levels, and reduced lymphocyte-eosinophil-lymphocyte ratio. These data may contribute to improving decision-making in the management of fatigue in patients with CD. |
| Publish Date |
2026-01-28 09:23 |
| Citation |
Morais TC, Couto G, Silva BCD, Lisbôa RA, da Cruz BS, Viana MGF, de Sousa GBC, Arenas LP, Nery ES, Fortes FML, de Almeida NP, Pimentel AM, Fontes JAM, Surlo VC, Chebli JF, Rocha R, Santana GO. Psychological and hematological factors associated with fatigue in patients with Crohn’s disease receiving pharmacological treatment. World J Gastroenterol 2026; 32(5): 115673 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i5/115673.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i5.115673 |
