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Articles Published Processes
2/3/2026 6:28:11 AM | Browse: 3 | Download: 29
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Received |
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2025-10-24 07:37 |
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Peer-Review Started |
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2025-10-24 07:37 |
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First Decision by Editorial Office Director |
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2025-11-14 01:51 |
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Return for Revision |
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2025-11-14 01:51 |
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Revised |
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2025-11-26 11:53 |
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Publication Fee Transferred |
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2025-12-04 10:33 |
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Second Decision by Editor |
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2025-12-22 02:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-22 07:09 |
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Articles in Press |
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2025-12-22 07:09 |
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Edit the Manuscript by Language Editor |
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2026-01-09 00:47 |
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Typeset the Manuscript |
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2026-01-27 00:37 |
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Publish the Manuscript Online |
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2026-02-03 06:28 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Increasing expression of presenilin 1, β-catenin and p-PTEN and its regulatory roles on cell invasion in gastric cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xi Lin, Guo-Feng Lin, Fei-Teng Gu and Yong-Liang Li |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Science and Technology Project of Putia |
2022S3F006 |
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| Corresponding Author |
Yong-Liang Li, Director, Department of Gastrointestinal Surgery, Affiliated Hospital of Putian University, No. 999 Dongzhen East Road, Licheng District, Putian 351100, Fujian Province, China. lx05942022@163.com |
| Key Words |
Gastric cancer; Presenilin 1; β-catenin; Phosphorylation of tensin homolog deleted on chromosome ten; Mechanisms of invasion |
| Core Tip |
The high expression of presenilin 1 was correlated with advanced tumor stages, and its expression was positively correlated with both expressions of β-catenin and phosphorylation of tensin homolog deleted on chromosome ten in patients with gastric cancer (GC). The regulation of phosphatase and tensin homolog deleted on chromosome ten phosphorylation and cytoplasmic localization by presenilin 1 through β-catenin, as a novel signal pathway of GC progression, could contribute to GC tumorigenesis. |
| Publish Date |
2026-02-03 06:28 |
| Citation |
Lin X, Lin GF, Gu FT, Li YL. Increasing expression of presenilin 1, β-catenin and p-PTEN and its regulatory roles on cell invasion in gastric cancer. World J Gastrointest Oncol 2026; 18(2): 115689 |
| URL |
https://www.wjgnet.com/1948-5204/full/v18/i2/115689.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v18.i2.115689 |
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