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Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 115698
Country China
Received
2025-10-24 06:49
Peer-Review Started
2025-10-24 06:49
First Decision by Editorial Office Director
2025-11-25 09:27
Return for Revision
2025-11-26 02:28
Revised
2025-12-04 10:32
Publication Fee Transferred
2025-12-05 10:13
Second Decision by Editor
2026-02-12 02:50
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-12 03:52
Articles in Press
2026-02-12 03:52
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-04-13 01:08
Publish the Manuscript Online
2026-04-24 10:11
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Case Report
Article Title Loop ileostomy-induced reversible nonalcoholic fatty liver disease in a rectal cancer patient: A case report and review of literature
Manuscript Source Unsolicited Manuscript
All Author List Yong-Kang Liang, Ju-He Zhang, Song Liang, Shen-Wei Wu and Xue-Yi Feng
ORCID
Author(s) ORCID Number
Yong-Kang Liang http://orcid.org/0009-0000-9040-3441
Xue-Yi Feng http://orcid.org/0009-0009-8524-7291
Funding Agency and Grant Number
Funding Agency Grant Number
Scientific Research Fund of Bengbu Medical University No. 2024byzd288
Corresponding Author Xue-Yi Feng, MD, PhD, Department of General Surgery, Lu’an Hospital of Anhui Medical University (Lu’an People’s Hospital of Anhui Province), No. 21 West Wanxi Road, Lu’an 237005, Anhui Province, China. fxy514270277@126.com
Key Words Nonalcoholic fatty liver disease; Rectal cancer; Loop ileostomy; Glucagon-like peptide 1; Peptide YY(3-36); Case report
Core Tip This case highlights a rare, reversible occurrence of nonalcoholic fatty liver disease following loop ileostomy in a rectal cancer patient. The temporal association between ileostomy, increased appetite, dyslipidemia, and fluctuations in glucagon-like peptide 1 and peptide YY(3-36) levels suggests a potential metabolic impact of ileostomy. These findings introduce a novel hypothesis linking gastrointestinal anatomical changes to hepatic lipid accumulation, warranting further mechanistic investigation.
Publish Date 2026-04-24 10:11
Citation

Liang YK, Zhang JH, Liang S, Wu SW, Feng XY. Loop ileostomy-induced reversible nonalcoholic fatty liver disease in a rectal cancer patient: A case report and review of literature. World J Gastrointest Surg 2026; 18(4): 115698

URL https://www.wjgnet.com/1948-9366/full/v18/i4/115698.htm
DOI https://dx.doi.org/10.4240/wjgs.v18.i4.115698
Full Article (PDF) WJGS-18-115698-with-cover.pdf
CARE Checklist–2016 115698-CARE-Checklist-2016.pdf
Manuscript File 115698_Auto_Edited_052237.docx
Answering Reviewers 115698-answering-reviewers.pdf
Audio Core Tip 115698-audio.MP3
Conflict-of-Interest Disclosure Form 115698-conflict-of-interest-statement.pdf
Copyright License Agreement 115698-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 115698-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 115698-non-native-speakers.pdf
Peer-review Report 115698-peer-reviews.pdf
Scientific Misconduct Check 115698-scientific-misconduct-check.png
Scientific Editor Work List 115698-scientific-editor-work-list.pdf
CrossCheck Report 115698-crosscheck-report.pdf