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Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 115706
Country China
Received
2025-12-16 08:47
Peer-Review Started
2025-12-16 08:47
First Decision by Editorial Office Director
2026-01-06 06:10
Return for Revision
2026-01-06 06:10
Revised
2026-01-12 13:43
Publication Fee Transferred
2026-01-18 09:49
Second Decision by Editor
2026-03-27 02:32
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-27 03:01
Articles in Press
2026-03-27 03:01
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-06-08 15:37
Publish the Manuscript Online
2026-06-24 09:14
ISSN 1948-9366 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Combined inflammatory markers and amylase levels for early detection of postoperative pancreatic fistula following laparoscopic pancreaticoduodenectomy
Manuscript Source Unsolicited Manuscript
All Author List Jian-Kang Yang, Ya-Qi Gu, Zong-Guo He and Fu-Bao Liu
ORCID
Author(s) ORCID Number
Fu-Bao Liu http://orcid.org/0009-0004-4982-899X
Funding Agency and Grant Number
Corresponding Author Fu-Bao Liu, Chief Physician, Department of Hepatobiliary and Pancreas Surgery, The First Affiliated Hospital of Anhui Medical University, Jiankang Road, Xiejiaji District, Hefei 235211, Anhui Province, China. 18155415185@163.com
Key Words Laparoscopic pancreaticoduodenectomy; Pancreatic fistula; Inflammatory markers; Amylase; Diagnostic accuracy
Core Tip Clinically relevant postoperative pancreatic fistula remains a major driver of morbidity after laparoscopic pancreaticoduodenectomy; early risk stratification is clinically meaningful. Amylase-related indices (drain fluid amylase concentration, serum amylase concentration, drain-to-serum amylase concentration ratio) reflect pancreatic leakage, while interleukin-6/interleukin-8/C-reactive protein reflect systemic inflammatory burden; combining them improves discrimination. A combined model incorporating amylase indices and inflammatory markers showed high areas under the receiver operating characteristic curve on postoperative day 1 and postoperative day 3, supporting early identification of high-risk patients.
Publish Date 2026-06-24 09:14
Citation

Yang JK, Gu YQ, He ZG, Liu FB. Combined inflammatory markers and amylase levels for early detection of postoperative pancreatic fistula following laparoscopic pancreaticoduodenectomy. World J Gastrointest Surg 2026; 18(6): 115706

URL https://www.wjgnet.com/1948-9366/full/v18/i6/115706.htm
DOI https://doi.org/10.4240/wjgs.115706
Full Article (PDF) WJGS-18-115706-with-cover.pdf
Manuscript File 115706_Auto_Edited-YJP.docx
Answering Reviewers 115706-answering-reviewers.pdf
Audio Core Tip 115706-audio.mp3
Biostatistics Review Certificate 115706-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 115706-conflict-of-interest-statement.pdf
Copyright License Agreement 115706-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 115706-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 115706-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 115706-non-native-speakers.pdf
Peer-review Report 115706-peer-reviews.pdf
Scientific Misconduct Check 115706-scientific-misconduct-check.png
Scientific Editor Work List 115706-scientific-editor-work-list.pdf
CrossCheck Report 115706-crosscheck-report.pdf