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5/26/2026 3:52:13 AM | Browse: 3 | Download: 0
Publication Name World Journal of Hepatology
Manuscript ID 115709
Country Italy
Received
2025-10-24 02:58
Peer-Review Started
2025-10-24 02:58
First Decision by Editorial Office Director
2025-12-25 08:37
Return for Revision
2025-12-25 16:32
Revised
2026-01-02 18:49
Publication Fee Transferred
Second Decision by Editor
2026-01-22 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-22 08:17
Articles in Press
2026-01-22 08:17
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-05-19 08:06
Publish the Manuscript Online
2026-05-26 03:52
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Infectious Diseases
Manuscript Type Correspondence
Article Title Letter to the Editor: From prediction to prevention: Integrating nomograms and pathogen biology in multidrug-resistant pyogenic liver abscess
Manuscript Source Invited Manuscript
All Author List Marco Fiore
ORCID
Author(s) ORCID Number
Marco Fiore http://orcid.org/0000-0001-7263-0229
Funding Agency and Grant Number
Corresponding Author Marco Fiore, Lecturer, MD, Professor, Department of Women, Child and General and Specialized Surgery, University of Campania “Luigi Vanvitelli”, Piazza Miraglia 2, Naples 80138, Italy. marco.fiore@unicampania.it
Key Words Critically ill patients; Pyogenic liver abscess; Multidrug-resistant Gram-negative bacteria; Predictive nomogram; Antimicrobial stewardship; Host-pathogen interaction
Core Tip Xu et al proposed a bedside nomogram to estimate the probability of multidrug-resistant (MDR) Gram-negative pyogenic liver abscess (PLA) using five routinely available variables. This letter clarifies how such risk stratification can be operationalized at the bedside through concrete clinical scenarios, while arguing that prediction becomes clinically meaningful only when coupled to actionable pathways: Early imaging and source control, rapid resistance-gene testing where available, guideline-concordant empiric coverage in high-risk patients, and stewardship-driven de-escalation. Integrating host vulnerability with pathogen biology may allow hepatology services to move from delayed recognition to prevention-oriented management of MDR-PLA.
Publish Date 2026-05-26 03:52
Citation

Fiore M. Letter to the Editor: From prediction to prevention: Integrating nomograms and pathogen biology in multidrug-resistant pyogenic liver abscess. World J Hepatol 2026; 18(5): 115709

URL https://www.wjgnet.com/1948-5182/full/v18/i5/115709.htm
DOI https://dx.doi.org/10.4254/wjh.v18.i5.115709
Full Article (PDF) WJH-18-115709-with-cover.pdf
Manuscript File 115709_Auto_Edited_075340.docx
Answering Reviewers 115709-answering-reviewers.pdf
Audio Core Tip 115709-audio.mp4
Conflict-of-Interest Disclosure Form 115709-conflict-of-interest-statement.pdf
Copyright License Agreement 115709-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 115709-non-native-speakers.pdf
Peer-review Report 115709-peer-reviews.pdf
Scientific Misconduct Check 115709-scientific-misconduct-check.png
Scientific Editor Work List 115709-scientific-editor-work-list.pdf
CrossCheck Report 115709-crosscheck-report.pdf