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3/27/2026 6:07:04 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 115710
Country China
Received
2025-10-24 09:43
Peer-Review Started
2025-10-24 09:44
First Decision by Editorial Office Director
2025-11-19 10:57
Return for Revision
2025-11-19 10:57
Revised
2025-12-01 16:49
Publication Fee Transferred
2025-12-03 16:10
Second Decision by Editor
2026-02-02 02:51
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-03 01:36
Articles in Press
2026-02-03 01:36
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-17 05:51
Publish the Manuscript Online
2026-03-27 06:07
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title MassARRAY-based KRAS and GNAS hotspot mutation analysis of cystic fluid enables accurate classification of pancreatic cystic lesions
Manuscript Source Unsolicited Manuscript
All Author List Wen-Fei Diao, Ming Cui, Tian-Qi Chen, Jin-Heng Xiao, Sen Yang, Qing-Yuan Zheng, Rui-Yuan Xu, Xian-Lin Han and Ya Hu
ORCID
Author(s) ORCID Number
Wen-Fei Diao http://orcid.org/0009-0007-4995-3450
Xian-Lin Han http://orcid.org/0000-0003-4083-3640
Ya Hu http://orcid.org/0000-0003-2813-9947
Funding Agency and Grant Number
Funding Agency Grant Number
Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences 2023-I2M-2-002
National High-Level Hospital Clinical Research Funding 2022-PUMCH-D-001
Peking Union Medical College Hospital Talent Cultivation Program UHB12625
Milstein Medical Asian American Partnership (MMAAP) Foundation
Noncommunicable Chronic Diseases-National Science and Technology Major Project 2025ZD0552402
Corresponding Author Ya Hu, MD, Professor, Department of General Surgery, Peking Union Medical College Hospital, No. 1 Shuaifuyuan, Dongcheng District, Beijing 100730, China. huya@pumch.cn
Key Words Pancreatic cyst lesions; Cyst fluid analysis; KRAS; GNAS; MassARRAY
Core Tip Pancreatic cystic lesions (PCLs) are highly heterogenous, which included benign, pre-malignant and malignant lesions. Current diagnostic approaches for PCLs exhibit limited efficacy and accuracy. The implementation of MassARRAY-based KRAS and GNAS mutation analysis of pancreatic cystic fluids improves the precise identification of mucinous cysts and intraductal papillary mucinous neoplasms, thereby providing critical support for clinical decision-making.
Publish Date 2026-03-27 06:07
Citation

Diao WF, Cui M, Chen TQ, Xiao JH, Yang S, Zheng QY, Xu RY, Han XL, Hu Y. MassARRAY-based KRAS and GNAS hotspot mutation analysis of cystic fluid enables accurate classification of pancreatic cystic lesions. World J Gastroenterol 2026; 32(13): 115710

URL https://www.wjgnet.com/1007-9327/full/v32/i13/115710.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i13.115710
Full Article (PDF) WJG-32-115710-with-cover.pdf
STROBE Statement 115710-STROBE-statement.pdf
Manuscript File 115710_Auto_Edited_070441.docx
Answering Reviewers 115710-answering-reviewers.pdf
Audio Core Tip 115710-audio.mp3
Biostatistics Review Certificate 115710-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 115710-conflict-of-interest-statement.pdf
Copyright License Agreement 115710-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 115710-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 115710-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 115710-non-native-speakers.pdf
Supplementary Material 115710-supplementary-material.pdf
Peer-review Report 115710-peer-reviews.pdf
Scientific Misconduct Check 115710-scientific-misconduct-check.png
Scientific Editor Work List 115710-scientific-editor-work-list.pdf
CrossCheck Report 115710-crosscheck-report.pdf