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Publication Name World Journal of Stem Cells
Manuscript ID 115733
Country India
Received
2025-10-24 08:01
Peer-Review Started
2025-10-24 08:01
First Decision by Editorial Office Director
2025-11-25 07:46
Return for Revision
2025-11-25 07:46
Revised
2025-11-30 04:17
Publication Fee Transferred
Second Decision by Editor
2026-01-13 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-14 09:09
Articles in Press
2026-01-14 09:09
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-04-07 09:34
Publish the Manuscript Online
2026-04-20 08:05
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell & Tissue Engineering
Manuscript Type Correspondence
Article Title Letter to the Editor: Advances in bioengineering and translational progress of stem cell-driven cartilage regeneration
Manuscript Source Unsolicited Manuscript
All Author List Sasi Nivruthi, Dilipkumar Preetha and Nagarajan Selvamurugan
ORCID
Author(s) ORCID Number
Nagarajan Selvamurugan http://orcid.org/0000-0003-3713-1920
Funding Agency and Grant Number
Corresponding Author Nagarajan Selvamurugan, PhD, Professor, Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur 603203, Tamil Nādu, India. selvamun@srmist.edu.in
Key Words Cartilage regeneration; Mesenchymal stem cells; Chondrocyte microenvironment; Chondrocyte hypertrophy; Clinical studies
Core Tip A review by Cong et al highlighted stem cell-driven cartilage regeneration. Stem cell-based strategies redefine cartilage repair by integrating the regenerative potential of stem cells with tissue-engineering innovations. However, a thorough understanding of the therapeutic potential of these strategies requires consideration of several key aspects. First, careful regulation of progenitor cell differentiation is essential to promote stable chondrocyte formation while preventing hypertrophy. Second, a thorough analysis of clinical studies is required to assess sample sizes and therapeutic efficacy compared with placebo controls. Third, the chondrocyte microenvironment that hosts the bioengineered materials must be addressed.
Publish Date 2026-04-20 08:05
Citation

Nivruthi S, Preetha D, Selvamurugan N. Letter to the Editor: Advances in bioengineering and translational progress of stem cell-driven cartilage regeneration. World J Stem Cells 2026; 18(4): 115733

URL https://www.wjgnet.com/1948-0210/full/v18/i4/115733.htm
DOI https://dx.doi.org/10.4252/wjsc.v18.i4.115733
Full Article (PDF) WJSC-18-115733-with-cover.pdf
Manuscript File 115733_Auto_Edited_132053-YJP.docx
Answering Reviewers 115733-answering-reviewers.pdf
Audio Core Tip 115733-audio.mp3
Conflict-of-Interest Disclosure Form 115733-conflict-of-interest-statement.pdf
Copyright License Agreement 115733-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 115733-non-native-speakers.pdf
Peer-review Report 115733-peer-reviews.pdf
Scientific Misconduct Check 115733-scientific-misconduct-check.png
Scientific Editor Work List 115733-scientific-editor-work-list.pdf
CrossCheck Report 115733-crosscheck-report.pdf