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3/27/2026 6:07:03 AM | Browse: 2 | Download: 13
Publication Name World Journal of Gastroenterology
Manuscript ID 115758
Country China
Received
2025-10-31 14:20
Peer-Review Started
2025-10-31 14:20
First Decision by Editorial Office Director
2025-11-06 09:43
Return for Revision
2025-11-06 09:43
Revised
2025-11-19 08:14
Publication Fee Transferred
2025-12-28 05:51
Second Decision by Editor
2026-01-21 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-21 07:50
Articles in Press
2026-01-21 07:50
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-28 09:48
Publish the Manuscript Online
2026-03-27 06:07
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Basic Study
Article Title Biological welding: A rapid and bloodless approach to hemorrhoidectomy
Manuscript Source Unsolicited Manuscript
All Author List Yuan Chen, Qian-Rui Zhang, Ming-Gan Guo, Zhong-Yi Sun and Fan-Chun Zeng
ORCID
Author(s) ORCID Number
Yuan Chen http://orcid.org/0009-0000-7163-2070
Qian-Rui Zhang http://orcid.org/0009-0005-9619-0949
Ming-Gan Guo http://orcid.org/0009-0007-5464-3836
Zhong-Yi Sun http://orcid.org/0009-0008-3397-721X
Fan-Chun Zeng http://orcid.org/0009-0001-6320-7020
Funding Agency and Grant Number
Funding Agency Grant Number
Shenzhen Science and Technology Program No. JCYJ20220531103004008
Talent Introduction Program of Renji Hospital Affiliated to Chongqing University No. 20251028-06
Medicine-Engineering Interdisciplinary Research Foundation of Shenzhen University No. 2023YG018
Corresponding Author Fan-Chun Zeng, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, No. 3688 Nanhai Avenue, Nanshan District, Shenzhen 518060, Guangdong Province, China. zengisle@szu.edu.cn
Key Words Biological welding; Hemorrhoidectomy; Surgical time; Blood loss; Recovery time; Pathological analysis
Core Tip This study demonstrates that biological welding technology, which integrates tissue fusion, cutting, and hemostasis into a single procedure, offers a rapid and bloodless approach to hemorrhoidectomy. In a rabbit model, it significantly reduced operative time by approximately 80%, achieved zero intraoperative blood loss, and accelerated postoperative recovery compared to traditional excision and suturing. Mechanistically, it promotes organized tissue repair by remodeling collagen fibers and reducing inflammation. These findings highlight its potential as a safe, efficient, and innovative surgical technique for clinical application in the treatment of hemorrhoids.
Publish Date 2026-03-27 06:07
Citation

Chen Y, Zhang QR, Guo MG, Sun ZY, Zeng FC. Biological welding: A rapid and bloodless approach to hemorrhoidectomy. World J Gastroenterol 2026; 32(13): 115758

URL https://www.wjgnet.com/1007-9327/full/v32/i13/115758.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i13.115758
Full Article (PDF) WJG-32-115758-with-cover.pdf
The ARRIVE Guidelines 115758-The-ARRIVE-Guidelines.pdf
Manuscript File 115758_Auto_Edited_063025.docx
Answering Reviewers 115758-answering-reviewers.pdf
Audio Core Tip 115758-audio.m4a
Biostatistics Review Certificate 115758-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 115758-conflict-of-interest-statement.pdf
Copyright License Agreement 115758-copyright-assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 115758-institutional-animal-care-and-use-committee-statement.pdf
Non-Native Speakers of English Editing Certificate 115758-non-native-speakers.pdf
Peer-review Report 115758-peer-reviews.pdf
Scientific Misconduct Check 115758-scientific-misconduct-check.png
Scientific Editor Work List 115758-scientific-editor-work-list.pdf
CrossCheck Report 115758-crosscheck-report.pdf