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2/12/2026 11:20:20 AM | Browse: 2 | Download: 26
Publication Name World Journal of Hepatology
Manuscript ID 115763
Country China
Received
2025-11-03 07:13
Peer-Review Started
2025-11-03 07:14
First Decision by Editorial Office Director
2025-11-10 07:02
Return for Revision
2025-11-10 07:02
Revised
2025-11-23 14:20
Publication Fee Transferred
2025-11-24 15:18
Second Decision by Editor
2025-12-24 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-25 03:51
Articles in Press
2025-12-25 03:51
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-29 01:02
Publish the Manuscript Online
2026-02-12 11:20
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Qushi Huoxue ointment ameliorates metabolic associated steatotic liver disease through autophagy activation and ferroptosis inhibition
Manuscript Source Unsolicited Manuscript
All Author List Yi-Yang Liu, Hong Qin, Hong-Xi Wu, Ru-Ting Wang, Qiu-Yan Yang, Feng Jiang, Xu-Dong Liu, De-Kun Wu and You-Ming Tang
ORCID
Author(s) ORCID Number
Yi-Yang Liu http://orcid.org/0009-0008-0067-5389
Hong-Xi Wu http://orcid.org/0009-0007-9258-139X
Feng Jiang http://orcid.org/0009-0005-7690-3403
Xu-Dong Liu http://orcid.org/0000-0003-1468-0484
De-Kun Wu http://orcid.org/0009-0002-3989-4534
You-Ming Tang http://orcid.org/0000-0002-5649-2273
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China (General Program) 82160837
Huatong Guokang Medical Research Special Project Grant 2023HT026
Innovation Project of Guangxi Graduate Education YCSW2024405
Corresponding Author De-Kun Wu, Teaching Experiment and Training Center, Guangxi University of Chinese Medicine, No. 179 Mingxiu East Road, Xixiangtang District, Nanning 530011, Guangxi Zhuang Autonomous Region, China. 1278323777@qq.com
Key Words Metabolic associated steatotic liver disease; Qushi Huoxue ointment; Autophagy; Ferroptosis; Lipid deposition
Core Tip Qushi Huoxue ointment can alleviate hepatic lipid accumulation, inflammation, and cell injury in metabolic associated steatotic liver disease mice. Our experimental evidence suggests that these therapeutic effects may be attributed to the concurrent activation of autophagy and inhibition of ferroptosis. The improvement in mitochondrial morphology and the presence of autophagosomes observed under the microscope provide morphological corroboration for this coordinated mechanism.
Publish Date 2026-02-12 11:20
Citation

Liu YY, Qin H, Wu HX, Wang RT, Yang QY, Jiang F, Liu XD, Wu DK, Tang YM. Qushi Huoxue ointment ameliorates metabolic associated steatotic liver disease through autophagy activation and ferroptosis inhibition. World J Hepatol 2026; 18(2): 115763

URL https://www.wjgnet.com/1948-5182/full/v18/i2/115763.htm
DOI https://dx.doi.org/10.4254/wjh.v18.i2.115763
Full Article (PDF) WJH-18-115763-with-cover.pdf
The ARRIVE Guidelines 115763-The-ARRIVE-Guidelines.pdf
Manuscript File 115763_Auto_Edited_094842.docx
Answering Reviewers 115763-answering-reviewers.pdf
Audio Core Tip 115763-audio.m4a
Biostatistics Review Certificate 115763-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 115763-conflict-of-interest-statement.pdf
Copyright License Agreement 115763-copyright-assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 115763-institutional-animal-care-and-use-committee-statement.pdf
Non-Native Speakers of English Editing Certificate 115763-non-native-speakers.pdf
Peer-review Report 115763-peer-reviews.pdf
Scientific Misconduct Check 115763-scientific-misconduct-check.png
Scientific Editor Work List 115763-scientific-editor-work-list.pdf
CrossCheck Report 115763-crosscheck-report.pdf